Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril

A E Gliddon; C J Doré; C M Black; Neil J McHugh; R Moots; C P Denton; A Herrick; T Barnes; J Camilleri; K Chakravarty; P Emery; B Griffiths; N D Hopkinson; P Hickling; P Lanyon; C Laversuch; T Lawson; R Mallya; M Nisar; C Rhys-Dillon; T Sheeran; P J Maddison

doi:10.1002/art.22965

Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril

A E Gliddon, C J Doré, C M Black, Neil J McHugh, R Moots, C P Denton, A Herrick, T Barnes, J Camilleri, K Chakravarty, P Emery, B Griffiths, N D Hopkinson, P Hickling, P Lanyon, C Laversuch, T Lawson, R Mallya, M Nisar, C Rhys-DillonT Sheeran, P J Maddison

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116 Citations (SciVal)

Abstract

Administration of quinapril for up to 3 years had no demonstrable effects on the occurrence of upper limb digital ulcers or on other vascular manifestations of lcSSc in this patient population.

Original language	English
Pages (from-to)	3837-46
Number of pages	10
Journal	Arthritis & Rheumatism
Volume	56
Issue number	11
DOIs	https://doi.org/10.1002/art.22965
Publication status	Published - 2007

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Gliddon, A. E., Doré, C. J., Black, C. M., McHugh, N. J., Moots, R., Denton, C. P., Herrick, A., Barnes, T., Camilleri, J., Chakravarty, K., Emery, P., Griffiths, B., Hopkinson, N. D., Hickling, P., Lanyon, P., Laversuch, C., Lawson, T., Mallya, R., Nisar, M., ... Maddison, P. J. (2007). Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril. Arthritis & Rheumatism, 56(11), 3837-46. https://doi.org/10.1002/art.22965

Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril. / Gliddon, A E; Doré, C J; Black, C M et al.
In: Arthritis & Rheumatism, Vol. 56, No. 11, 2007, p. 3837-46.

Research output: Contribution to journal › Article › peer-review

Gliddon, AE, Doré, CJ, Black, CM, McHugh, NJ, Moots, R, Denton, CP, Herrick, A, Barnes, T, Camilleri, J, Chakravarty, K, Emery, P, Griffiths, B, Hopkinson, ND, Hickling, P, Lanyon, P, Laversuch, C, Lawson, T, Mallya, R, Nisar, M, Rhys-Dillon, C, Sheeran, T & Maddison, PJ 2007, 'Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril', Arthritis & Rheumatism, vol. 56, no. 11, pp. 3837-46. https://doi.org/10.1002/art.22965

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abstract = "Administration of quinapril for up to 3 years had no demonstrable effects on the occurrence of upper limb digital ulcers or on other vascular manifestations of lcSSc in this patient population.",

author = "Gliddon, \{A E\} and Dor{\'e}, \{C J\} and Black, \{C M\} and McHugh, \{Neil J\} and R Moots and Denton, \{C P\} and A Herrick and T Barnes and J Camilleri and K Chakravarty and P Emery and B Griffiths and Hopkinson, \{N D\} and P Hickling and P Lanyon and C Laversuch and T Lawson and R Mallya and M Nisar and C Rhys-Dillon and T Sheeran and Maddison, \{P J\}",

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AU - Doré, C J

AU - Black, C M

AU - McHugh, Neil J

AU - Moots, R

AU - Denton, C P

AU - Herrick, A

AU - Barnes, T

AU - Camilleri, J

AU - Chakravarty, K

AU - Emery, P

AU - Griffiths, B

AU - Hopkinson, N D

AU - Hickling, P

AU - Lanyon, P

AU - Laversuch, C

AU - Lawson, T

AU - Mallya, R

AU - Nisar, M

AU - Rhys-Dillon, C

AU - Sheeran, T

AU - Maddison, P J

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N2 - Administration of quinapril for up to 3 years had no demonstrable effects on the occurrence of upper limb digital ulcers or on other vascular manifestations of lcSSc in this patient population.

AB - Administration of quinapril for up to 3 years had no demonstrable effects on the occurrence of upper limb digital ulcers or on other vascular manifestations of lcSSc in this patient population.

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Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril

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