Preschool hyperactivity specifically elevates long-term mental health risks more strongly in males than females: a prospective longitudinal study through to young adulthood

Elizabeth Smith, Brenda J. Meyer, Johanna Koerting, Cathy Laver-Bradbury, Louise Lee, Harriet Jefferson, Kapil Sayal, Luke Treglown, Margaret Thompson, Edmund J. S. Sonuga-Barke

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Evidence of continuities between preschool hyperactivity and adult mental health problems highlights the potential value of targeting early identification and intervention strategies. However, specific risk factors are currently unclear. This large-scale prospective longitudinal study aimed to identify which hyperactive preschoolers are at the greatest long-term risk of poor mental health. One hundred and seventy children (89 females) rated as hyperactive by their parents, and 88 non-hyperactive controls (48 females) were identified from a community sample of 4215 3-year-olds. Baseline data relating to behavioral/emotional problems and background characteristics were collected. Follow-up mental health and functional impairment outcomes were collected between 14 and 25 years of age. At age 3 years, males and females in the hyperactive group had similarly raised levels of hyperactivity and other behavior problems. In adolescence/young adulthood, these individuals showed elevated symptoms of ADHD, conduct disorder, mood disorder, anxiety and autism, as well as functional impairment. Preschool hyperactivity was strongly predictive of poor adolescent/adult outcomes for males across domains with effects being specifically driven by hyperactivity. For females, the effects of preschool hyperactivity were smaller and dropped to non-significant levels when other preschool problems were taken into account. Environmental risk factors also differed between the sexes, although these may also have been mediated by genetic risk. In conclusion, these results demonstrate marked sex differences in preschool predictors of later adolescent/adult mental health problems. Future research should include a measure of preschool inattention as well as hyperactivity. The findings highlight the potential value of tailored approaches to early identification strategies.

Original languageEnglish
Pages (from-to)123-136
Number of pages14
JournalEuropean Child & Adolescent Psychiatry
Volume26
Issue number1
Early online date13 Jun 2016
DOIs
Publication statusPublished - Jan 2017

Keywords

  • Long-term risk
  • Longitudinal study
  • Mental health
  • Preschool hyperactivity

Fingerprint Dive into the research topics of 'Preschool hyperactivity specifically elevates long-term mental health risks more strongly in males than females: a prospective longitudinal study through to young adulthood'. Together they form a unique fingerprint.

Cite this