Preparation of core-shell silver/silica nanopaticles and their application for enhancement of cyanine 3 fluorescence

N. Sui, V. Monnier, Z. Yang, Y. Chevolot, E. Laurenceau, E. Souteyrand, V. Dugas

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Core shell Ag@SiO 2-Streptavidin-Cy3 nanoparticles were prepared. Ag@SiO 2 nanoparticles were synthesized via a solgel method. Then, Streptavidin-Cy3 was covalently bonded to the Ag@SiO 2 surface. These core-shell nanoparticles were characterized by steady-state fluorescence spectroscopy and fluorescence scanning. In presence of the silver core, a 2.5-time enhancement of Cy3 fluorescence intensity was obtained. This result shows that these nanoparticles can be potentially helpful in surface analysis based on biochip. © 2012 World Scientific Publishing Company.
Original languageEnglish
Article number1240020
JournalInternational Journal of Nanoscience
Issue number4
Publication statusPublished - Aug 2012



  • Ag@SiO 2
  • Fluorescence
  • Surface enhancement

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