Core shell Ag@SiO 2-Streptavidin-Cy3 nanoparticles were prepared. Ag@SiO 2 nanoparticles were synthesized via a solgel method. Then, Streptavidin-Cy3 was covalently bonded to the Ag@SiO 2 surface. These core-shell nanoparticles were characterized by steady-state fluorescence spectroscopy and fluorescence scanning. In presence of the silver core, a 2.5-time enhancement of Cy3 fluorescence intensity was obtained. This result shows that these nanoparticles can be potentially helpful in surface analysis based on biochip. © 2012 World Scientific Publishing Company.
- Ag@SiO 2
- Surface enhancement