Preparation and characterisation of octenyl succinate starch as a delivery carrier for bioactive food components

Xueyu Wang, Xiaoxi Li, Ling Chen, Fengwei Xie, Long Yu, Bing Li

Research output: Contribution to journalArticlepeer-review

136 Citations (SciVal)

Abstract

The octenyl succinic anhydride (OSA) modified corn starch (OSAS) was synthesised with different degrees of substitution (DS) and the influences of three factors namely OSA/starch ratio, reaction temperature, and reaction time on the DS of OSAS were studied by response surface methodology (RSM). As a delivery carrier material, the characteristics of OSAS were investigated. The resistant starch (RS) content of OSAS was increased with increasing DS, indicating the improvement of colon-targeting property. The swelling ratio (SR) of the OSAS in simulated gastrointestinal fluids was higher than that of native starch and its hydrophilicity was decreased with increasing DS. For in vitro release study, the percentage of released bioactive components was less than 7% within the first 8 h and close to 100% over a period of 36 h when the DS was 0.60. These results demonstrate that OSAS can be a potential carrier for colon-targeted delivery of bioactive food components.

Original languageEnglish
Pages (from-to)1218-1225
Number of pages8
JournalFood Chemistry
Volume126
Issue number3
Early online date7 Dec 2010
DOIs
Publication statusPublished - 1 Jun 2011

Keywords

  • Bioactive food components
  • Delivery carrier
  • Esterification
  • Octenyl succinate starch

ASJC Scopus subject areas

  • Analytical Chemistry
  • Food Science

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