Potentiometric detection of protein interactions with peptide aptamers

Pedro Estrela, D Paul, P Migliorato, P Ko Ferrigno, L Wang, E Huq

Research output: Chapter or section in a book/report/conference proceedingChapter in a published conference proceeding

4 Citations (SciVal)

Abstract

Label-free electrical detection of protein interactions has been achieved by direct measurement of variations in open circuit potential using an accurate differential voltage measurement as well as field-effect transistors. Our model system involves a panel of peptide aptamers that recognise specific protein partners of the cyclin-dependent kinase family, which are relevant to cancer research applications.
Original languageEnglish
Title of host publicationProceedings of IEEE SENSORS 2008 Conference
PublisherIEEE
Pages646-649
Number of pages4
ISBN (Print)9781424425808
DOIs
Publication statusPublished - Oct 2008

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