Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors

Jingjing Gong, Seshasailam Venkateswaran, Michael G. Tanner, James M. Stone, Mark Bradley

Research output: Contribution to journalArticle

4 Citations (Scopus)
49 Downloads (Pure)

Abstract

Polymer microarrays were utilized for the high-throughput screening and discovery of optimal polymeric substrates capable of trapping functional ratiometric fluorescence-based pH sensors. This led to the identification of poly(methyl methacrylate-co-2-(dimethylamino) ethyl acrylate) (PA101), which allowed, via dip coating, the attachment of fluorescent pH sensors onto the tips of optical fibers, resulting in robust, rapid, and reproducible sensing of physiological pHs.

Original languageEnglish
Pages (from-to)417-424
Number of pages8
JournalACS Combinatorial Science
Volume21
Issue number5
Early online date11 Apr 2019
DOIs
Publication statusPublished - 13 May 2019

Keywords

  • high-throughput screening
  • optical fiber
  • pH sensor
  • polymer microarray

ASJC Scopus subject areas

  • Chemistry(all)

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