Plasma deposited metal Schiff-base compounds as antimicrobials

Neil Poulter, Matthew Donaldson, Geraldine Mulley, Luis Duque, Nicholas Waterfield, Alex G Shard, Steve Spencer, A Toby A Jenkins, Andrew L Johnson

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial efficacy of the two compounds were observed, suggesting possible mechanisms for antimicrobial activity. The ZSB system was plasma deposited under various pulse conditions onto non-woven fabric, and the antimicrobial efficacy of the resultant film measured for Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest the potential utility of this compound as an effective antimicrobial thin film, and confirm the critical role the ligands play in effecting antimicrobial activity.
Original languageEnglish
Pages (from-to)1477-1484
Number of pages8
JournalNew Journal of Chemistry
Volume35
Issue number7
DOIs
Publication statusPublished - 2011

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    Poulter, N., Donaldson, M., Mulley, G., Duque, L., Waterfield, N., Shard, A. G., Spencer, S., Jenkins, A. T. A., & Johnson, A. L. (2011). Plasma deposited metal Schiff-base compounds as antimicrobials. New Journal of Chemistry, 35(7), 1477-1484. https://doi.org/10.1039/C1NJ20091G