PirAB Toxin from Photorhabdus asymbiotica as a Larvicide against Dengue Vectors

A Ahantarig, N Chantawat, Nicholas R Waterfield, R Ffrench-Constant, P Kittayapong

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)


We have evaluated Photorhabdus insect-related protein (Pir) from Photorhabdus asymbiotica against dengue vectors. PirAB shows larvicidal activity against both Aedes aegypti and Aedes albopictus larvae but did not affect the Mesocyclops thermocyclopoides predator. PirAB expressed the strongest toxicity compared to PirA, PirB, or the mixture of PirA plus PirB. Whether the presence of an enterobacterial repetitive intergenic consensus sequence in PirAB, but not in PirA, PirB, or the mixture of PirA plus PirB, has any impact on biological control efficacy needs further investigation.
Original languageEnglish
Pages (from-to)4627-4629
Number of pages3
JournalApplied and Environmental Microbiology
Issue number13
Publication statusPublished - 2009

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