The human heart is responsible for maintaining constant, pulsatile blood flow in the human body. Mock circulatory loops (MCLs) have long been used as the mechanical representations of the human cardiovascular system and as test beds for mechanical circulatory support (MCS) devices and other interventional medical devices. This technology could also be used as a training and educational tool for surgeons/clinicians. To ensure the MCL can accurately simulate the pulsatile human cardiovascular system, it is essential that the MCL can reproduce human physiological responses, e.g., the Frank-Starling Mechanism, in a controllable operating environment. In this study, by using an elastance function template to control the simulated left ventricle, we created controllable pulsatile physiological flow in a 3D printed silicone vascular structure to successfully simulate the hemodynamic environment of the human cardiovascular system.
|Publication status||Acceptance date - 7 Apr 2022|
|Event||44th International Engineering in Medicine and Biology Conference - Glasgow, Glasgow, UK United Kingdom|
Duration: 11 Jul 2022 → 15 Jul 2022
|Conference||44th International Engineering in Medicine and Biology Conference|
|Abbreviated title||EMBC 2022|
|Country/Territory||UK United Kingdom|
|Period||11/07/22 → 15/07/22|