Phenol-soluble modulins, hellhounds from the staphylococcal virulence-factor pandemonium

Eleni Tsompanidou, Emma L Denham, Jan Maarten van Dijl

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Phenol-soluble modulins are secreted peptides with multiple functions in Staphylococcus aureus pathogenesis and spreading. Recent studies by Otto and coworkers show that these hellhounds of the staphylococcal virulence-factor pandemonium are unleashed through an essential ABC transporter, which represents an exciting new target for stopping the spread of this important pathogen.

Original languageEnglish
Pages (from-to)313-315
Number of pages3
JournalTrends in Microbiology
Volume21
Issue number7
DOIs
Publication statusPublished - Jul 2013

Keywords

  • ATP-Binding Cassette Transporters/metabolism
  • Animals
  • Bacterial Toxins/metabolism
  • Humans
  • Staphylococcal Skin Infections/microbiology
  • Staphylococcus aureus/pathogenicity

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