Abstract
Summary This chapter contains sections titled: The Neurophysiological Basis for Nicotine Addiction Genetic Variation and Smoking Predisposition Alleles Affecting Central Dopaminergic Function The Relationship Between Genetically Determined Variants of Cytochrome P450 Enzymes and Tobacco Dependence Future Targets for Candidate Gene Studies Genome Scans to Investigate Tobacco Dependence Genomic Areas Linked with Susceptibility to Nicotine Dependence Biallelic or Multiallelic Markers for Linkage Studies? Genome Scans in the Future Evidence for the Genomic Basis of Nicotine Addiction from Animal Models Applying Pharmacogenomics to Therapy for Nicotine Addiction Mechanism of Action of Existing Treatments and New Directions for Drug Therapy Classifying Smokers According to the Molecular Basis for their Habit Accurate Determination of Dosage for Therapeutic Interventions “Minimum SNP Set” for Tobacco Dependence and Need for High-Throughput Genotyping
| Original language | English |
|---|---|
| Title of host publication | Pharmacogenomics |
| Publisher | John Wiley & Sons, Ltd |
| Chapter | 22 |
| Pages | 443-460 |
| Number of pages | 18 |
| ISBN (Print) | 9783527600755 |
| DOIs | |
| Publication status | Published - 26 Mar 2002 |
Keywords
- pharmacogenomics
- tobacco addiction
- nicotine addiction
- smoking predisposition
- central dopaminergic function
- cytochrome P450 enzymes
- candidate gene
- genome scans
- markers
- therapy
- smokers
