Pharmaceutical process modelling

S A MacGregor; L B Newnes; J N Staniforth; R C Lamming; M J Tobyn; M Li; G R Kay; M D Horrill; D W Hajee

Pharmaceutical process modelling

S A MacGregor, L B Newnes, J N Staniforth, R C Lamming, M J Tobyn, M Li, G R Kay, M D Horrill, D W Hajee

Research output: Contribution to conference › Paper › peer-review

Abstract

The use of Computational Fluid Dynamics in the design of a pharmaceutical processor is described. A simple computational model of the process, was developed using a single phase flow. The results of this preliminary study showed good agreement with experimental tests. The model was further developed to consider the effect of solid particles on the process occuring within a single vessel pharmaceutical processor. Having obtained converged solutions the model was used to optimise the design of the processor. The desing optimisation was done on the basis of comparisons with conventional pharmaceutical processing equipment. Optimisation of the process parameters are important as they are known to affect the functionality of the final product

Original language	English
Pages	438-444
Number of pages	7
Publication status	Published - 1996
Event	International Conference on Process Modelling - Cottbus, Germany Duration: 1 Jan 1996 → …

Conference

Conference	International Conference on Process Modelling
Country/Territory	Germany
City	Cottbus
Period	1/01/96 → …

Cite this

@conference{3c77ecea06a146058affe9aae610b4a5,

title = "Pharmaceutical process modelling",

abstract = "The use of Computational Fluid Dynamics in the design of a pharmaceutical processor is described. A simple computational model of the process, was developed using a single phase flow. The results of this preliminary study showed good agreement with experimental tests. The model was further developed to consider the effect of solid particles on the process occuring within a single vessel pharmaceutical processor. Having obtained converged solutions the model was used to optimise the design of the processor. The desing optimisation was done on the basis of comparisons with conventional pharmaceutical processing equipment. Optimisation of the process parameters are important as they are known to affect the functionality of the final product",

author = "MacGregor, {S A} and Newnes, {L B} and Staniforth, {J N} and Lamming, {R C} and Tobyn, {M J} and M Li and Kay, {G R} and Horrill, {M D} and Hajee, {D W}",

year = "1996",

language = "English",

pages = "438--444",

note = "International Conference on Process Modelling ; Conference date: 01-01-1996",

}

TY - CONF

T1 - Pharmaceutical process modelling

AU - MacGregor, S A

AU - Newnes, L B

AU - Staniforth, J N

AU - Lamming, R C

AU - Tobyn, M J

AU - Li, M

AU - Kay, G R

AU - Horrill, M D

AU - Hajee, D W

PY - 1996

Y1 - 1996

N2 - The use of Computational Fluid Dynamics in the design of a pharmaceutical processor is described. A simple computational model of the process, was developed using a single phase flow. The results of this preliminary study showed good agreement with experimental tests. The model was further developed to consider the effect of solid particles on the process occuring within a single vessel pharmaceutical processor. Having obtained converged solutions the model was used to optimise the design of the processor. The desing optimisation was done on the basis of comparisons with conventional pharmaceutical processing equipment. Optimisation of the process parameters are important as they are known to affect the functionality of the final product

AB - The use of Computational Fluid Dynamics in the design of a pharmaceutical processor is described. A simple computational model of the process, was developed using a single phase flow. The results of this preliminary study showed good agreement with experimental tests. The model was further developed to consider the effect of solid particles on the process occuring within a single vessel pharmaceutical processor. Having obtained converged solutions the model was used to optimise the design of the processor. The desing optimisation was done on the basis of comparisons with conventional pharmaceutical processing equipment. Optimisation of the process parameters are important as they are known to affect the functionality of the final product

M3 - Paper

SP - 438

EP - 444

T2 - International Conference on Process Modelling

Y2 - 1 January 1996

ER -

Pharmaceutical process modelling

Abstract

Conference

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