Peptide-mediated cell delivery: Application in protein target validation

Research output: Contribution to journalReview articlepeer-review

175 Citations (SciVal)

Abstract

Recent reports have suggested that conjugation of peptides, proteins and antisense to short highly basic peptides, such as TAT, antennapedia and transportan, results in their rapid translocation into cells. Importantly, these conjugates have been shown to exert actions in a number of animal models suggesting their general utility for the determination of protein function in vitro and in vivo.

Original languageEnglish
Pages (from-to)587-594
Number of pages8
JournalCurrent Opinion in Pharmacology
Volume2
Issue number5
DOIs
Publication statusPublished - 1 Oct 2002

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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