“Pattern regulation in epimorphic fields”, aka the polar coordinate model

Research output: Contribution to journalArticlepeer-review

Abstract

The Polar Coordinate Model (PCM) was a model, published in 1976, to account for the properties of distal regeneration in the appendages of insects and vertebrates. It had considerable impact at the time and has continued to be cited ever since. This article describes the work that led up to the model, the genesis of the model itself, its strengths and weaknesses, and its long term impact.

Original languageEnglish
Pages (from-to)82-90
Number of pages9
JournalDevelopmental Biology
Volume520
Early online date9 Jan 2025
DOIs
Publication statusE-pub ahead of print - 9 Jan 2025

Data Availability Statement

No data was used for the research described in the article.

Funding

No funding acknowledged

Keywords

  • Cockroach
  • Cricket
  • Drosophila
  • Limb regeneration
  • Newt
  • Polar coordinate model
  • Positional information
  • Regeneration

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

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