Patient perceptions of the Raynaud's Condition Score diary provide insight into its performance in clinical trials of Raynaud's phenomenon: Comment on the Article by Denton et al

John D Pauling, Lesley A Saketkoo, Robyn T Domsic

Research output: Contribution to journalLetter

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The recent report by Denton et al. [1] adds to previous well-designed negative placebo-controlled clinical trials of Raynaud's phenomenon (RP) in systemic sclerosis (SSc). The primary endpoint was the weekly average number of RP attacks, with secondary endpoints including daily RP attack duration and RP severity (the single-item Raynaud's Condition Score [RCS]), that together comprise the RCS diary. The accompanying editorial, provides insightful suppositions of factors contributing to the disappointing performance of the RCS diary in clinical trials [2].

Original languageEnglish
Pages (from-to)973-974
Number of pages2
JournalArthritis & Rheumatology
Issue number6
Early online date7 Mar 2018
Publication statusPublished - 1 Jun 2018



  • Letter

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology

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