Pathbase: A new reference resource and database for laboratory mouse pathology

P N Schofield, J B L Bard, J Boniver, V Covelli, P Delvenne, M Ellender, W Engstrom, W Goessner, M Gruenberger, H Hoefler, J W Hopewell, M Mancuso, C Mothersill, L Quintanilla-Martinez, B Rozell, H Sariola, J P Sundberg, A Ward

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.
Original languageEnglish
Pages (from-to)525-528
Number of pages4
JournalRadiation Protection Dosimetry
Volume112
Issue number4
DOIs
Publication statusPublished - 2004

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