Pathbase: A new reference resource and database for laboratory mouse pathology

P N Schofield; J B L Bard; J Boniver; V Covelli; P Delvenne; M Ellender; W Engstrom; W Goessner; M Gruenberger; H Hoefler; J W Hopewell; M Mancuso; C Mothersill; L Quintanilla-Martinez; B Rozell; H Sariola; J P Sundberg; A Ward

doi:10.1093/rpd/nch101

Pathbase: A new reference resource and database for laboratory mouse pathology

P N Schofield, J B L Bard, J Boniver, V Covelli, P Delvenne, M Ellender, W Engstrom, W Goessner, M Gruenberger, H Hoefler, J W Hopewell, M Mancuso, C Mothersill, L Quintanilla-Martinez, B Rozell, H Sariola, J P Sundberg, A Ward

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

19 Citations (SciVal)

Abstract

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

Original language	English
Pages (from-to)	525-528
Number of pages	4
Journal	Radiation Protection Dosimetry
Volume	112
Issue number	4
DOIs	https://doi.org/10.1093/rpd/nch101
Publication status	Published - 2004

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ID number: ISI:000226515600011

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Schofield, P. N., Bard, J. B. L., Boniver, J., Covelli, V., Delvenne, P., Ellender, M., Engstrom, W., Goessner, W., Gruenberger, M., Hoefler, H., Hopewell, J. W., Mancuso, M., Mothersill, C., Quintanilla-Martinez, L., Rozell, B., Sariola, H., Sundberg, J. P., & Ward, A. (2004). Pathbase: A new reference resource and database for laboratory mouse pathology. Radiation Protection Dosimetry, 112(4), 525-528. https://doi.org/10.1093/rpd/nch101

Schofield, PN, Bard, JBL, Boniver, J, Covelli, V, Delvenne, P, Ellender, M, Engstrom, W, Goessner, W, Gruenberger, M, Hoefler, H, Hopewell, JW, Mancuso, M, Mothersill, C, Quintanilla-Martinez, L, Rozell, B, Sariola, H, Sundberg, JP & Ward, A 2004, 'Pathbase: A new reference resource and database for laboratory mouse pathology', Radiation Protection Dosimetry, vol. 112, no. 4, pp. 525-528. https://doi.org/10.1093/rpd/nch101

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AU - Schofield, P N

AU - Bard, J B L

AU - Boniver, J

AU - Covelli, V

AU - Delvenne, P

AU - Ellender, M

AU - Engstrom, W

AU - Goessner, W

AU - Gruenberger, M

AU - Hoefler, H

AU - Hopewell, J W

AU - Mancuso, M

AU - Mothersill, C

AU - Quintanilla-Martinez, L

AU - Rozell, B

AU - Sariola, H

AU - Sundberg, J P

AU - Ward, A

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AB - Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

U2 - 10.1093/rpd/nch101

DO - 10.1093/rpd/nch101

M3 - Article

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EP - 528

JO - Radiation Protection Dosimetry

JF - Radiation Protection Dosimetry

IS - 4

ER -

Pathbase: A new reference resource and database for laboratory mouse pathology

Abstract

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