TY - JOUR
T1 - Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate
AU - Pula, Giordano
AU - Garonna, Elena
AU - Dunn, Warwick B
AU - Hirano, Michio
AU - Pizzorno, Giuseppe
AU - Campanella, Michelangelo
AU - Schwartz, Edward L
AU - El Kouni, Mahmoud H
AU - Wheeler-Jones, Caroline P D
PY - 2010
Y1 - 2010
N2 - Platelet-derived dRP stimulates endothelial cell migration by upregulating integrin β(3) in a reactive oxygen species-dependent manner. As demonstrated by our in vivo experiments, this novel paracrine regulatory pathway is likely to play an important role in the stimulation of angiogenesis by platelets.
AB - Platelet-derived dRP stimulates endothelial cell migration by upregulating integrin β(3) in a reactive oxygen species-dependent manner. As demonstrated by our in vivo experiments, this novel paracrine regulatory pathway is likely to play an important role in the stimulation of angiogenesis by platelets.
UR - http://www.scopus.com/inward/record.url?scp=78650420402&partnerID=8YFLogxK
UR - http://dx.doi.org/10.1161/ATVBAHA.110.215855
U2 - 10.1161/ATVBAHA.110.215855
DO - 10.1161/ATVBAHA.110.215855
M3 - Article
SN - 1524-4636
VL - 30
SP - 2631
EP - 2638
JO - Arteriosclerosis, thrombosis, and vascular biology
JF - Arteriosclerosis, thrombosis, and vascular biology
IS - 12
ER -