Platelet-derived dRP stimulates endothelial cell migration by upregulating integrin β(3) in a reactive oxygen species-dependent manner. As demonstrated by our in vivo experiments, this novel paracrine regulatory pathway is likely to play an important role in the stimulation of angiogenesis by platelets.
|Number of pages||8|
|Journal||Arteriosclerosis, thrombosis, and vascular biology|
|Publication status||Published - 2010|