Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide

Marco Santonastaso; Simon J Freakley; Peter J Miedziak; Gemma L Brett; Jennifer K Edwards; Graham J Hutchings

doi:10.1021/op500195e

Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide

Marco Santonastaso, Simon J Freakley, Peter J Miedziak, Gemma L Brett, Jennifer K Edwards, Graham J Hutchings

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

23 Citations (SciVal)

Abstract

Catalysts containing bimetallic gold–palladium nanoparticles are extremely active and selective for the oxidation of alcohols to aldehydes and the direct synthesis of hydrogen peroxide from molecular hydrogen and oxygen. We show that the oxidation of benzyl alcohol can be carried out at 50 °C and below by generating hydrogen peroxide in situ. The oxidation of benzyl alcohol to benzaldehyde has been achieved with high selectivity (>85%) at temperatures where no reaction is observed with only molecular oxygen in an autoclave. The effect of temperature, catalyst support, and solvent are studied in an autoclave system and reactions were carried out in a fixed bed reactor at a range of gas flow rates where the catalysts demonstrated stable conversion and selectivity.

Original language	English
Pages (from-to)	1455-1460
Number of pages	6
Journal	Organic Process Research & Development
Volume	18
Issue number	11
Early online date	29 Aug 2014
DOIs	https://doi.org/10.1021/op500195e
Publication status	Published - 1 Nov 2014

Access to Document

10.1021/op500195e

Cite this

@article{c43d21c155434cb8864aeb801ea815a6,

title = "Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide",

abstract = "Catalysts containing bimetallic gold–palladium nanoparticles are extremely active and selective for the oxidation of alcohols to aldehydes and the direct synthesis of hydrogen peroxide from molecular hydrogen and oxygen. We show that the oxidation of benzyl alcohol can be carried out at 50 °C and below by generating hydrogen peroxide in situ. The oxidation of benzyl alcohol to benzaldehyde has been achieved with high selectivity (>85%) at temperatures where no reaction is observed with only molecular oxygen in an autoclave. The effect of temperature, catalyst support, and solvent are studied in an autoclave system and reactions were carried out in a fixed bed reactor at a range of gas flow rates where the catalysts demonstrated stable conversion and selectivity.",

author = "Marco Santonastaso and Freakley, {Simon J} and Miedziak, {Peter J} and Brett, {Gemma L} and Edwards, {Jennifer K} and Hutchings, {Graham J}",

year = "2014",

month = nov,

day = "1",

doi = "10.1021/op500195e",

language = "English",

volume = "18",

pages = "1455--1460",

journal = "Organic Process Research & Development",

issn = "1083-6160",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide

AU - Santonastaso, Marco

AU - Freakley, Simon J

AU - Miedziak, Peter J

AU - Brett, Gemma L

AU - Edwards, Jennifer K

AU - Hutchings, Graham J

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Catalysts containing bimetallic gold–palladium nanoparticles are extremely active and selective for the oxidation of alcohols to aldehydes and the direct synthesis of hydrogen peroxide from molecular hydrogen and oxygen. We show that the oxidation of benzyl alcohol can be carried out at 50 °C and below by generating hydrogen peroxide in situ. The oxidation of benzyl alcohol to benzaldehyde has been achieved with high selectivity (>85%) at temperatures where no reaction is observed with only molecular oxygen in an autoclave. The effect of temperature, catalyst support, and solvent are studied in an autoclave system and reactions were carried out in a fixed bed reactor at a range of gas flow rates where the catalysts demonstrated stable conversion and selectivity.

AB - Catalysts containing bimetallic gold–palladium nanoparticles are extremely active and selective for the oxidation of alcohols to aldehydes and the direct synthesis of hydrogen peroxide from molecular hydrogen and oxygen. We show that the oxidation of benzyl alcohol can be carried out at 50 °C and below by generating hydrogen peroxide in situ. The oxidation of benzyl alcohol to benzaldehyde has been achieved with high selectivity (>85%) at temperatures where no reaction is observed with only molecular oxygen in an autoclave. The effect of temperature, catalyst support, and solvent are studied in an autoclave system and reactions were carried out in a fixed bed reactor at a range of gas flow rates where the catalysts demonstrated stable conversion and selectivity.

U2 - 10.1021/op500195e

DO - 10.1021/op500195e

M3 - Article

SN - 1083-6160

VL - 18

SP - 1455

EP - 1460

JO - Organic Process Research & Development

JF - Organic Process Research & Development

IS - 11

ER -

Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide

Abstract

Access to Document

Fingerprint

Cite this