Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide

Marco Santonastaso, Simon J Freakley, Peter J Miedziak, Gemma L Brett, Jennifer K Edwards, Graham J Hutchings

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Abstract

Catalysts containing bimetallic gold–palladium nanoparticles are extremely active and selective for the oxidation of alcohols to aldehydes and the direct synthesis of hydrogen peroxide from molecular hydrogen and oxygen. We show that the oxidation of benzyl alcohol can be carried out at 50 °C and below by generating hydrogen peroxide in situ. The oxidation of benzyl alcohol to benzaldehyde has been achieved with high selectivity (>85%) at temperatures where no reaction is observed with only molecular oxygen in an autoclave. The effect of temperature, catalyst support, and solvent are studied in an autoclave system and reactions were carried out in a fixed bed reactor at a range of gas flow rates where the catalysts demonstrated stable conversion and selectivity.
Original languageEnglish
Pages (from-to)1455-1460
Number of pages6
JournalOrganic Process Research & Development
Volume18
Issue number11
Early online date29 Aug 2014
DOIs
Publication statusPublished - 1 Nov 2014

Cite this

Santonastaso, M., Freakley, S. J., Miedziak, P. J., Brett, G. L., Edwards, J. K., & Hutchings, G. J. (2014). Oxidation of Benzyl Alcohol using in Situ Generated Hydrogen Peroxide. Organic Process Research & Development, 18(11), 1455-1460. https://doi.org/10.1021/op500195e