Organocatalytic Synthesis of Fused Bicyclic 2,3-Dihydro-1,3,4-oxadiazoles through an Intramolecular Cascade Cyclization

Alison J. Fugard, Bethany K. Thompson, Alexandra M.Z. Slawin, James E. Taylor, Andrew D. Smith

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Hydrazone-carboxylic acids undergo intramolecular cyclization in the presence of pivaloyl chloride, iPr2NEt, and catalytic DABCO to form a range of substituted fused tricyclic 2,3-dihydro-1,3,4-oxadiazoles in high yields.

Original languageEnglish
Pages (from-to)5824-5827
Number of pages4
JournalOrganic Letters
Volume17
Issue number23
DOIs
Publication statusPublished - 24 Nov 2015

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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