Important features for flow chemistry systems are a narrow residence time distribution, appropriate sample volume and small pressure drop. These criteria were evaluated by studying hydrodynamic characteristics of tubular microflow systems using Computational Fluid Dynamics and experimental tracing breakthrough curves in a novel multi-bore Microcapillary Film Reactor (MFR). The inner diameter and diffusion coefficient of molecular species had a large influence on approaching ideal plug flow. Compared to a single large bore capillary (2400 μm i.d.), the MFR (363±32.2 μm) provides opportunity for improving product yields via excellent radial mixing whilst exhibiting all desired qualities for a high-performance flow system.
|Number of pages||2|
|Publication status||Published - 7 Oct 2019|
|Event||23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences - Conference Centre Basel, Basel, Switzerland|
Duration: 27 Oct 2019 → 31 Oct 2019
|Conference||23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences|
|Abbreviated title||MicroTAS 2019|
|Period||27/10/19 → 31/10/19|
- Tubular microflow
- Residence time distribution
- Microcapillary Film Reactor
- Flow Reactor
Gill, K., Masoudi, D., Narayanasamy, S., Hester, P., Estrela, P., & Reis, N. (2019). Optimizing residence time distribution in capillary-based systems using computational fluid dynamic simulations. Paper presented at 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences , Basel, Switzerland.