Abstract

Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).
Original languageEnglish
Number of pages1
Publication statusPublished - Jul 2017
Event23rd Congress of the European Society of Biomechanics - Escuela Tecnica Superior de Ingeniena, Unversidad de Sevilla, Seville, Spain
Duration: 2 Jul 20175 Jul 2017
https://esbiomech.org/conference/index.php/esb2017/seville

Conference

Conference23rd Congress of the European Society of Biomechanics
CountrySpain
CitySeville
Period2/07/175/07/17
Internet address

Fingerprint

Shear stress
Blood
Fluid dynamics
Strain rate
Numerical models
Computational fluid dynamics
Pumps
Experiments

Cite this

NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES. / Khoo, Dominica Pi Ying; Gill, Harinderjit; Cookson, Andrew; Fraser, Katharine.

2017. Abstract from 23rd Congress of the European Society of Biomechanics, Seville, Spain.

Research output: Contribution to conferenceAbstract

Khoo, DPY, Gill, H, Cookson, A & Fraser, K 2017, 'NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES' 23rd Congress of the European Society of Biomechanics, Seville, Spain, 2/07/17 - 5/07/17, .
Khoo DPY, Gill H, Cookson A, Fraser K. NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES. 2017. Abstract from 23rd Congress of the European Society of Biomechanics, Seville, Spain.
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abstract = "Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).",
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T1 - NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES

AU - Khoo, Dominica Pi Ying

AU - Gill, Harinderjit

AU - Cookson, Andrew

AU - Fraser, Katharine

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N2 - Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).

AB - Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).

M3 - Abstract

ER -