NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES

Dominica Pi Ying Khoo; Harinderjit Gill; Andrew Cookson; Katharine Fraser

NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES

Dominica Pi Ying Khoo, Harinderjit Gill, Andrew Cookson, Katharine Fraser

Research output: Contribution to conference › Abstract

Abstract

Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).

Original language	English
Number of pages	1
Publication status	Published - Jul 2017
Event	23rd Congress of the European Society of Biomechanics - Escuela Tecnica Superior de Ingeniena, Unversidad de Sevilla, Seville, Spain Duration: 2 Jul 2017 → 5 Jul 2017 https://esbiomech.org/conference/index.php/esb2017/seville

Conference

Conference	23rd Congress of the European Society of Biomechanics
Country	Spain
City	Seville
Period	2/07/17 → 5/07/17
Internet address	https://esbiomech.org/conference/index.php/esb2017/seville

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Khoo, D. P. Y., Gill, H., Cookson, A., & Fraser, K. (2017). NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES. Abstract from 23rd Congress of the European Society of Biomechanics, Seville, Spain.

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title = "NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES",

abstract = "Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).",

author = "Khoo, {Dominica Pi Ying} and Harinderjit Gill and Andrew Cookson and Katharine Fraser",

year = "2017",

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language = "English",

note = "23rd Congress of the European Society of Biomechanics ; Conference date: 02-07-2017 Through 05-07-2017",

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T1 - NUMERICAL COMPARISON OF SHEAR AND ELONGATIONAL STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES

AU - Khoo, Dominica Pi Ying

AU - Gill, Harinderjit

AU - Cookson, Andrew

AU - Fraser, Katharine

PY - 2017/7

Y1 - 2017/7

N2 - Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).

AB - Introduction Ventricular Assist Devices (VADs) are becoming the gold standard treatment for end stage heart failure [1]. However, many of these post-surgical complications are related to damage to the blood components by the fluid dynamic stress in the mechanical pump. To date, most numerical models for blood damage are functions of the scalar shear stress (SSS) [2], the second invariant of the strain rate, Sij, in analogy with von Mises Stress. Since rotary VADs are assumed to exert mainly shear stress, the data for these models is obtained from Taylor-Couette flow experiments which create shear stress on the blood. However, alternative experimental data show the existence of elongational stress alongside shear stress that deform cells differently [3]. So the aim of this work was to assess the accuracy of the assumption and significance of elongational stress, in comparison with shear stress in rotary VADs using computational fluid dynamics (CFD).

M3 - Abstract

ER -