NOVEL OPIOID COMPOUNDS AND THEIR USES

John Lewis (Inventor), Stephen Husbands (Inventor), Larry Toll (Inventor)

Research output: Patent

Abstract

The present invention relates to opioid compounds, especially to C14 esters and ethers of naltrexone and analogues thereof. The present invention also relates to compositions, methods and medical uses that employ such compounds. More specifically, the present invention pertains to compounds of formula: and to their use in the treatment of diseases and disorders including pain, hyperalgesia, addiction, substance abuse disorders, stress, anorexia, anxiety, depression, cough, asthma, hypertension, gastrointestinal motility disorder, water retention, cognitive disorders, and locomotor disorders.
Original languageEnglish
Patent numberWO2015082932 (A1)
Priority date2/12/13
Filing date5/12/14
Publication statusPublished - 11 Jun 2015

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