Abstract
The present invention relates to opioid compounds, especially to C14 esters and ethers of naltrexone and analogues thereof. The present invention also relates to compositions, methods and medical uses that employ such compounds. More specifically, the present invention pertains to compounds of formula: and to their use in the treatment of diseases and disorders including pain, hyperalgesia, addiction, substance abuse disorders, stress, anorexia, anxiety, depression, cough, asthma, hypertension, gastrointestinal motility disorder, water retention, cognitive disorders, and locomotor disorders.
Original language | English |
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Patent number | WO2015082932 (A1) |
IPC | A61K31/439,A61P25/24,A61P25/30,C07D489/02 |
Priority date | 5/12/13 |
Filing date | 5/12/14 |
Publication status | Published - 11 Jun 2015 |
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MC2- Nuclear Magnetic Resonance (NMR)
Material and Chemical Characterisation (MC2)Facility/equipment: Technology type