Novel autoantibodies and clinical phenotypes in adult and juvenile myositis

Zoe E Betteridge, Harsha Gunawardena, Neil J McHugh

Research output: Contribution to journalArticlepeer-review

81 Citations (Scopus)

Abstract

Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositisspecific autoantibodies, with particular attention to the recently identified and characterized novel myositis autoantibodies: p155/140, p140 (MJ), CADM-140 (MDA5), SAE, and 200/100.
Original languageEnglish
Article number209
JournalArthritis Research & Therapy
Volume13
Issue number2
DOIs
Publication statusPublished - 2011

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