TY - JOUR
T1 - Novel autoantibodies and clinical phenotypes in adult and juvenile myositis
AU - Betteridge, Zoe E
AU - Gunawardena, Harsha
AU - McHugh, Neil J
PY - 2011
Y1 - 2011
N2 - Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositisspecific autoantibodies, with particular attention to the recently identified and characterized novel myositis autoantibodies: p155/140, p140 (MJ), CADM-140 (MDA5), SAE, and 200/100.
AB - Autoantibodies targeting intracellular proteins involved in key processes are detected in patients with idiopathic inflammatory myopathies. These myositisspecific autoantibodies have been increasingly demonstrated to correlate with distinct clinical phenotypes within the myositis spectrum. This review highlights the clinical associations of the myositisspecific autoantibodies, with particular attention to the recently identified and characterized novel myositis autoantibodies: p155/140, p140 (MJ), CADM-140 (MDA5), SAE, and 200/100.
UR - http://www.scopus.com/inward/record.url?scp=80053231155&partnerID=8YFLogxK
UR - http://arthritis-research.com/content/13/2/209
UR - http://dx.doi.org/10.1186/ar3275
U2 - 10.1186/ar3275
DO - 10.1186/ar3275
M3 - Article
SN - 1478-6362
VL - 13
JO - Arthritis Research & Therapy
JF - Arthritis Research & Therapy
IS - 2
M1 - 209
ER -