Novel Aryl and Heteroaryl Acyl Sulfamide Synthesis via Microwave-Assisted Palladium-Catalyzed Carbonylation

Bryan Roberts, David Liptrot, Lilian Alcaraz

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

A novel, simple synthesis of aryl and heteroaryl acyl sulfamides has been developed via palladium-catalyzed carbonylation of aryl or heteroaryl halides in the presence of sulfamide nucleophiles. A range of reactions illustrating the wide scope of this reaction was carried out under microwave irradiation in a vessel equipped with a gas inlet adapter and proceeded in good to excellent yields.
Original languageEnglish
Pages (from-to)1264-1267
Number of pages4
JournalOrganic Letters
Volume12
Issue number6
DOIs
Publication statusPublished - 19 Mar 2010

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