New iterative cone beam CT reconstruction software: parameter optimisation and convergence study

Wei Qiu, Jenna Tong, Cathryn Mitchell, T Marchant, Paul Spencer, C J Moore, Manuchehr Soleimani

Research output: Contribution to journalArticlepeer-review

13 Citations (SciVal)


Cone beam computed tomography (CBCT) provides a volumetric image reconstruction from tomographic projection data. Image quality is the main concern for reconstruction in comparison to conventional CT. The reconstruction algorithm used is clearly important and should be carefully designed, developed and investigated before it can be applied clinically. The Multi-Instrument Data Analysis System (MIDAS) tomography software originally designed for geophysical applications has been modified to CBCT image reconstruction. In CBCT reconstruction algorithms, iterative methods offer the potential to generate high quality images and would be an advantage especially for limited projection data. In this paper detailed studies of the CBCT iterative algorithms encapsulated in MIDAS are presented.Stability, convergence rate, quality of reconstructed image and edge recovery are suggested as the main criteria for monitoring reconstructive performance. Accordingly, the selection of relaxation parameter and number of iterations are studied in detail. Results are presented, where images are reconstructed from full and limited but evenly sampled cone beam CT projection data using iterative algorithms. Various iterative algorithms have been implemented and the best selection of the iteration number and relaxation parameters are investigated for ART. Optimal parameters are chosen where the errors in projected data as well as image errors are minimal.
Original languageEnglish
Pages (from-to)166-174
Number of pages9
JournalComputer Methods and Programs in Biomedicine
Issue number2
Publication statusPublished - Nov 2010


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