Abstract
Objective: To conduct meta-analyses of neuropsychological performance in young people with type 1 diabetes. Methods: Meta-analysis of 24 studies. Studies published between 1980 and 2005 were identified. The inclusion criteria were: young people who were less than =19 years of age with type 1 diabetes, a case-control design and standardized neuropsychological tests of seven cognitive domains.
Results: Diabetes was statistically associated with poorer performance on visuospatial ability (d = -0.29), motor speed (d = -0.26) and writing (d = -0.28), on sustained attention (d = -0.21) and reading (d = -0.23). Smaller effects were identified on full IQ (d = -0.14), on performance (d = -0.18) and verbal IQ (d = -0.15). Severe hypoglycemia was linked to deficits in short-term verbal memory (d = -0.14; Confidence Interval: -0.318, 0.024; p = .04).
Conclusions: This meta-analysis indicates that children with type 1 diabetes have mild cognitive impairments and subtly reduced overall intellectual functioning.
Results: Diabetes was statistically associated with poorer performance on visuospatial ability (d = -0.29), motor speed (d = -0.26) and writing (d = -0.28), on sustained attention (d = -0.21) and reading (d = -0.23). Smaller effects were identified on full IQ (d = -0.14), on performance (d = -0.18) and verbal IQ (d = -0.15). Severe hypoglycemia was linked to deficits in short-term verbal memory (d = -0.14; Confidence Interval: -0.318, 0.024; p = .04).
Conclusions: This meta-analysis indicates that children with type 1 diabetes have mild cognitive impairments and subtly reduced overall intellectual functioning.
| Original language | English |
|---|---|
| Pages (from-to) | 271-282 |
| Number of pages | 12 |
| Journal | Journal of Pediatric Psychology |
| Volume | 34 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2009 |
