Abstract
2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time-consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal parametrization of complex-valued images, jointly modeling magnitude and phase across multiple echoes to enable velocity estimation, and leveraging their inductive bias for the reconstruction of the velocity data. Additionally, to compensate for the oversmoothing tendency observed in neural-field reconstructions under severe undersampling, a simple voxel-based postprocessing step is introduced. The method is validated numerically in Cartesian and radial k-space with both high and low temporal resolution data. This approach achieves accurate reconstructions at high acceleration factors, with low errors even at 32 (Formula presented.) and 64 (Formula presented.) undersampling for the high temporal resolution data, and 16 (Formula presented.) for the low temporal resolution data, and consistently outperforms classical locally low-rank regularized voxel-based methods in both flow estimates and anatomical depiction.
| Original language | English |
|---|---|
| Article number | e19788 |
| Journal | Advanced Science |
| Early online date | 3 Feb 2026 |
| DOIs | |
| Publication status | E-pub ahead of print - 3 Feb 2026 |
Data Availability Statement
The data supporting the findings of this study include (i) patient MRI scans acquired on a GE HealthCare scanner, which are publicly available on Zenodo [38], and (ii) publicly available data from the CMRxRecon 2024 challenge, which can be accessed directly from the official challenge repository https://cmrxrecon.github.io/2024/Home.html. The code developed for this study is publicly available at https://github.com/parratia/PC-MRI-with-Neural-Fields.Funding
PA is supported by a scholarship from the EPSRC Centre for Doctoral Training in Statistical Applied Mathematics at Bath (SAMBa), under the project EP/S022945/1. MJE acknowledges support from the EPSRC (EP/T026693/1, EP/V026259/1, EP/Y037286/1). MM acknowledges support from Cancer Research UK Cambridge Centre [CTRQQR‐2021/100012] and Cambridge Experimental Cancer Medicine Centre (ECMC) [ECMCQQR‐2022/100003]. CBS acknowledges support from the Royal Society Wolfson Fellowship, the EPSRC advanced career fellowship EP/V029428/1, the EPSRC programme grant EP/V026259/1, the Wellcome Innovator Awards 215733/Z/19/Z and 221633/Z/20/Z, the EPSRC funded ProbAI hub EP/Y028783/1. MJE and CBS also acknowledge support from the European Union Horizon 2020 research and innovation programme under the Marie Skłdowska‐Curie grant agreement REMODEL. This research was also supported by the NIHR Cambridge Biomedical Research Centre (NIHR203312). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.
| Funders | Funder number |
|---|---|
| Cambridge Experimental Cancer Medicine Centre | |
| Horizon 2020 Framework Programme | |
| Engineering and Physical Sciences Research Council | EP/V026259/1, EP/Y037286/1, EP/T026693/1 |
| Cancer Research UK Cambridge Institute, University of Cambridge | CTRQQR‐2021/100012 |
| NIHR Cambridge Biomedical Research Centre | NIHR203312 |
| Centre for Doctoral Training in Statistical Applied Mathematics, University of Bath | EP/S022945/1 |
| Wellcome | EP/Y028783/1, 215733/Z/19/Z, 221633/Z/20/Z |
| Royal Society | EP/V029428/1 |
| Imperial Experimental Cancer Medicine Centre | ECMCQQR‐2022/100003 |
Keywords
- 2D cine phase contrast MRI
- 2D flow MRI
- neural fields
- undersampled k-space
ASJC Scopus subject areas
- Medicine (miscellaneous)
- General Chemical Engineering
- Biochemistry, Genetics and Molecular Biology (miscellaneous)
- General Materials Science
- General Engineering
- General Physics and Astronomy
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