Near-Infrared Light-Triggered Bacterial Eradication Using a Nanowire Nanocomposite of Graphene Nanoribbons and Chitosan-Coated Silver Nanoparticles

Ming Zhou, Hui Qi Gan, Guo Rong Chen, Tony D. James, Bin Zhang, Qiang Hu, Fugui Xu, Xi Le Hu, Xiao Peng He, Yiyong Mai

Research output: Contribution to journalArticlepeer-review

1 Citation (SciVal)

Abstract

Bacterial infection is a major threat to human health. However, many antibacterial agents currently used are severely limited due to drug-resistance, and the development of side effects. Herein, we have developed a non-antibiotic nanocomposite consisting of chitosan (ChS) coated silver nanoparticles (AgNPs) and graphene nanoribbon (GNR)-based nanowires for light-triggered eradication of bacteria. The presence of AgNP/ChS significantly enhanced the interactions of the GNR nanowires with Pseudomonas aeruginosa, a clinically common Gram-negative bacterium. Which enables the highly effective photothermal eradication of bacteria by GNR upon near-infrared light irradiation. The nanocomposite was shown to be applicable for the light-triggered eradication of bacterial biofilms and the inhibition of bacterial growth on medical patches used for abdominal-wall hernia surgery.

Original languageEnglish
Article number767847
JournalFrontiers in Chemistry
Volume9
DOIs
Publication statusPublished - 27 Oct 2021

Keywords

  • antibiotic
  • chitosan
  • graphene nanoribbons
  • nanocomposite
  • silver nanoparticles

ASJC Scopus subject areas

  • Chemistry(all)

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