The highly porous nature of metal-organic frameworks (MOFs) offers great potential for the delivery of therapeutic agents. Here, we show that highly porous metal-organic frameworks can be used to deliver multiple therapeutic agents - a biologically active gas, an antibiotic drug molecule, and an active metal ion - simultaneously but at different rates. The possibilities offered by delivery of multiple agents with different mechanisms of action and, in particular, variable timescales may allow new therapy approaches. Here, we show that the loaded MOFs are highly active against various strains of bacteria.
|Early online date||Dec 2014|
|Publication status||Published - 1 Jan 2015|
ASJC Scopus subject areas
- Materials Science(all)
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- Department of Chemical Engineering - Director of Teaching
- Centre for Sustainable and Circular Technologies (CSCT)
- EPSRC Centre for Doctoral Training in Statistical Applied Mathematics (SAMBa)
- Centre for Integrated Materials, Processes & Structures (IMPS) - Centre Director
Person: Research & Teaching, Core staff