Multiplexed photoluminescent sensors: Towards improved disease diagnostics

Xiao Peng He, Xi Le Hu, Tony D. James, Juyoung Yoon, He Tian

Research output: Contribution to journalReview articlepeer-review

75 Citations (Scopus)

Abstract

The ability to simultaneously monitor multiple analytes in, for example, a single microplate well, is important for both basic research and clinical applications. In particular, for disease diagnosis there is a growing awareness that determination of a single disease biomarker is insufficient to pathologically confirm a disease state. Consequently, much recent literature has been directed towards the development of multiplexed photoluminescent sensors which can simultaneously detect multiple and diverse biomarkers that exist in a homogenous solution or a single cell, accelerating the progress towards precise disease diagnosis. This tutorial review highlights a selection of recent contributions towards this emerging interdisciplinary field that incorporates chemistry, chemical biology, materials sciences and medical sciences.

Original languageEnglish
Pages (from-to)6687-6696
Number of pages10
JournalChemical Society Reviews
Volume46
Issue number22
Early online date25 Aug 2017
DOIs
Publication statusPublished - 21 Nov 2017

ASJC Scopus subject areas

  • Chemistry(all)

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