Abstract
Two apparently linked fatal cases of pneumococcal meningitis were investigated. Pneumolysin PCR performed on blood and cerebrospinal fluid was positive in a culture-negative case. A second case yielded Streptococcus pneumoniae from blood culture. Multilocus sequence typing performed on DNA extracted from case 1 (specimens) and case 2 (isolate) revealed identical sequence types (ST53) substantiating the link between them.
| Original language | English |
|---|---|
| Pages (from-to) | 2004-2008 |
| Number of pages | 5 |
| Journal | Journal of Clinical Microbiology |
| Volume | 43 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2005 |
Bibliographical note
Birtles, Andrew McCarthy, Noel Sheppard, Carmen L Rutter, Harry Guiver, Malcolm Haworth, Elizabeth George, Robert C eng Case Reports Research Support, Non-U.S. Gov't 2005/04/09 09:00 J Clin Microbiol. 2005 Apr;43(4):2004-8.Keywords
- Adult Bacterial Proteins/*genetics Bacterial Typing Techniques Blood/microbiology Cerebrospinal Fluid/microbiology Fatal Outcome *Homeless Persons Humans Male Meningitis, Pneumococcal/*microbiology Polymerase Chain Reaction *Sequence Analysis, DNA Streptococcus pneumoniae/*classification/genetics/isolation & purification Streptolysins/*genetics
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