Multifaceted catalysis approach to nitrile activation: direct synthesis of halogenated allyl amides from allylic alcohols.

Roy P. Lester, Jay J. Dunsford, Jason E. Camp

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Allyl amides were synthesized from the reaction of allyl alcs. and halogenated nitriles using a platinum multifaceted catalysis approach in which both the nucleophilic addn. and subsequent [3,3]-sigmatropic rearrangement steps of the process were catalyzed by the same complex. Addnl., 1H/13C{1H} NMR and GC studies provided the first insights into the mechanism of this transformation. [on SciFinder(R)]
Original languageEnglish
Pages (from-to)7472-7476
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume11
Issue number43
DOIs
Publication statusPublished - 26 Sep 2013

Keywords

  • halogenated nitrile allyl alc nucleophilic addn sigmatropic rearrangement mechanism
  • allyl amide halogenated prepn multifaceted platinum catalyst

Fingerprint

Dive into the research topics of 'Multifaceted catalysis approach to nitrile activation: direct synthesis of halogenated allyl amides from allylic alcohols.'. Together they form a unique fingerprint.

Cite this