Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach

Victor Castro-Gutierrez, Francis Hassard, Milan Vu, Rodrigo Leitao, Beata Burczynska, Dirk Wildeboer, Isobelle Stanton, Shadi Rahimzadeh, Gianluca Baio, Hemda Garelick, Jan Hofman, Barbara Kasprzyk-Hordern, Rachel Kwiatkowska, Azeem Majeed, Sally Priest, Jasmine M S Grimsley, Lian Lundy, Andrew Singer, Mariachiara Di Cesare

Research output: Contribution to journalArticlepeer-review

18 Citations (SciVal)


Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.

Original languageEnglish
Article numbere0270168
JournalPLoS ONE
Issue number6 June
Publication statusPublished - 17 Jun 2022

ASJC Scopus subject areas

  • General


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