Abstract
As the COVID-19 pandemic continues to escalate globally and acquires new mutations, accurate diagnostic technologies continue to play a vital role in controlling and understanding the epidemiology of this disease. A plethora of technologies have enabled the diagnosis of individuals, informed clinical management, aided population-wide screening to determine transmission rates and identified cases within the wider community and high-risk settings. This review explores the application of molecular diagnostics technologies in controlling the spread of COVID-19, and the key factors that affect the sensitivity and specificity of the tests used.
Original language | English |
---|---|
Pages (from-to) | 3744-3763 |
Number of pages | 20 |
Journal | Analytical Methods |
Volume | 13 |
Issue number | 34 |
Early online date | 5 Aug 2021 |
DOIs | |
Publication status | Published - 14 Sept 2021 |
Bibliographical note
Funding Information:Dr Hannah S. Leese is an assis- tant professor in the Department of Chemical Engineering at the University of Bath and leading the Materials for Health Lab. She received her Ph.D. in Chemical Engineering from the University of Bath and was post- doctoral research associate at Imperial College London (2013– 2017) and the University of Manchester (2017–2018). Han- nah's current research focus includes microneedle biosensors, molecularly imprinted polymers for disease detection, and therapeutic textiles supported by EPSRC, the Royal Society and CRUK.
Publisher Copyright:
© The Royal Society of Chemistry.