Microsphere Solid-State Biolasers

Van Duong Ta; Soraya Caixeiro; Francisco M. Fernandes; Riccardo Sapienza

doi:10.1002/adom.201601022

Microsphere Solid-State Biolasers

Van Duong Ta, Soraya Caixeiro, Francisco M. Fernandes, Riccardo Sapienza

Department of Physics

Research output: Contribution to journal › Article › peer-review

40 Citations (SciVal)

Abstract

Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid-state microspheres with diameters of 15–100 µm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few µJ mm^–2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.

Original language	English
Article number	1601022
Journal	Advanced Optical Materials
Volume	5
Issue number	8
DOIs	https://doi.org/10.1002/adom.201601022
Publication status	Published - 18 Apr 2017

Bibliographical note

Funding Information:
This work was funded by the Engineering and Physical Sciences Research Council (EPSRC) under grant EP/M027961/1, the Leverhulme Trust (RPG-2014-238), and the Royal Society (RG140457).

Publisher Copyright:
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Funding

This work was funded by the Engineering and Physical Sciences Research Council (EPSRC) under grant EP/M027961/1, the Leverhulme Trust (RPG-2014-238), and the Royal Society (RG140457).

Keywords

biomaterial
lasers
polysaccharides
protein
whispering gallery mode

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics

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10.1002/adom.201601022Licence: CC BY

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title = "Microsphere Solid-State Biolasers",

abstract = "Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid-state microspheres with diameters of 15–100 µm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few µJ mm–2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.",

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AU - Caixeiro, Soraya

AU - Fernandes, Francisco M.

AU - Sapienza, Riccardo

N1 - Funding Information: This work was funded by the Engineering and Physical Sciences Research Council (EPSRC) under grant EP/M027961/1, the Leverhulme Trust (RPG-2014-238), and the Royal Society (RG140457). Publisher Copyright: © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

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AB - Biolasers obtained from biomaterials are attracting a wealth of interest for their potential as future biosensors with enhanced sensitivity, and advanced cell tracking. Here, miniature biolasers are reported, which are formed by bovine serum albumin (BSA) protein and biosourced polysaccharides derived from land plants such as cellulose and pectin. Using a green processing route aided by simple emulsions, solid-state microspheres with diameters of 15–100 µm are fabricated and utilized as whispering gallery mode lasers with thresholds of a few µJ mm–2 and quality factors of up to 3000. Furthermore, BSA microlasers are found to be compatible with cell growth and resistant to the aqueous environment of cell culture media. This environmentally friendly and biocompatible design shows promise for future implantable biosensing devices opening a path between laser science and medicine.

KW - biomaterial

KW - lasers

KW - polysaccharides

KW - protein

KW - whispering gallery mode

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ER -

Microsphere Solid-State Biolasers

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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