Abstract
The direct epoxidation of olefins using monooxygenases offers the realistic prospect of stoichiometric conversion of a pro-chiral substrate into an enantiomerically pure product. A number of microbial systems are available in which the mechanism of oxygen activation, and consequently the oxygen reactivity, differs. This paper discusses some of the merits and potential problems associated with these different systems.
Original language | English |
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Pages (from-to) | 211-218 |
Number of pages | 8 |
Journal | Biocatalysis and Biotransformation |
Volume | 10 |
Issue number | 1-4 |
DOIs | |
Publication status | Published - 1 Jan 1994 |
Keywords
- Alkane monooxygenase
- Alkene monooxygenase
- Epoxide
- Microbial oxidation
ASJC Scopus subject areas
- Biotechnology
- Catalysis
- Biochemistry