Method for non-invasively determining the relative levels of two biological substances. B1

Maria Delgado-Charro (Inventor), Richard Guy (Inventor)

Research output: Patent

Abstract

The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged substances from said biological system, and collecting said substances, analysing the collected amount of a first extracted substance and a second extracted substance and determining the extraction ratio of the first substance to the second substance to determine their relative levels in the biological system. When the first and second substances are both analytes susceptible to changes in their concentration in the biological system, this method provides information about the relative concentrations of the two substances in the biological system. When the first substance is an analyte susceptible to changes in its concentration in the biological system and the second substance has a substantially constant concentration in the biological system, the second subtance acts as an internal standard and the extraction ratio becomes a direct measurement of the physiological level of the first substance in the biological system. A iontophoretic sampling device for monitoring the relative levels of two substances present in a biological system is also disclosed.
Original languageEnglish
Patent number EP1401532 (WO03000340)
IPC A61N1/30; (IPC1-7): A61N1/30
Priority date22/06/01
Filing date17/06/02
Publication statusPublished - 10 Oct 2012

Cite this

Delgado-Charro, M., & Guy, R. (2012). IPC No. A61N1/30; (IPC1-7): A61N1/30. Method for non-invasively determining the relative levels of two biological substances. B1. (Patent No. EP1401532 (WO03000340)).

Method for non-invasively determining the relative levels of two biological substances. B1. / Delgado-Charro, Maria (Inventor); Guy, Richard (Inventor).

IPC No.: A61N1/30; (IPC1-7): A61N1/30. Patent No.: EP1401532 (WO03000340). Jun 17, 2002.

Research output: Patent

Delgado-Charro, M & Guy, R Jun. 17 2002, Method for non-invasively determining the relative levels of two biological substances. B1, Patent No. EP1401532 (WO03000340), IPC No. A61N1/30; (IPC1-7): A61N1/30.
@misc{2fea1829beba4dbdbb304d57a6e6ad42,
title = "Method for non-invasively determining the relative levels of two biological substances. B1",
abstract = "The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged substances from said biological system, and collecting said substances, analysing the collected amount of a first extracted substance and a second extracted substance and determining the extraction ratio of the first substance to the second substance to determine their relative levels in the biological system. When the first and second substances are both analytes susceptible to changes in their concentration in the biological system, this method provides information about the relative concentrations of the two substances in the biological system. When the first substance is an analyte susceptible to changes in its concentration in the biological system and the second substance has a substantially constant concentration in the biological system, the second subtance acts as an internal standard and the extraction ratio becomes a direct measurement of the physiological level of the first substance in the biological system. A iontophoretic sampling device for monitoring the relative levels of two substances present in a biological system is also disclosed.",
author = "Maria Delgado-Charro and Richard Guy",
year = "2012",
month = "10",
day = "10",
language = "English",
type = "Patent",
note = "EP1401532 (WO03000340); A61N1/30; (IPC1-7): A61N1/30",

}

TY - PAT

T1 - Method for non-invasively determining the relative levels of two biological substances. B1

AU - Delgado-Charro, Maria

AU - Guy, Richard

PY - 2012/10/10

Y1 - 2012/10/10

N2 - The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged substances from said biological system, and collecting said substances, analysing the collected amount of a first extracted substance and a second extracted substance and determining the extraction ratio of the first substance to the second substance to determine their relative levels in the biological system. When the first and second substances are both analytes susceptible to changes in their concentration in the biological system, this method provides information about the relative concentrations of the two substances in the biological system. When the first substance is an analyte susceptible to changes in its concentration in the biological system and the second substance has a substantially constant concentration in the biological system, the second subtance acts as an internal standard and the extraction ratio becomes a direct measurement of the physiological level of the first substance in the biological system. A iontophoretic sampling device for monitoring the relative levels of two substances present in a biological system is also disclosed.

AB - The method for non-invasively determining the relative levels of two substances present in a biological system includes the steps of extracting by reverse iontophoresis charged and uncharged substances from said biological system, and collecting said substances, analysing the collected amount of a first extracted substance and a second extracted substance and determining the extraction ratio of the first substance to the second substance to determine their relative levels in the biological system. When the first and second substances are both analytes susceptible to changes in their concentration in the biological system, this method provides information about the relative concentrations of the two substances in the biological system. When the first substance is an analyte susceptible to changes in its concentration in the biological system and the second substance has a substantially constant concentration in the biological system, the second subtance acts as an internal standard and the extraction ratio becomes a direct measurement of the physiological level of the first substance in the biological system. A iontophoretic sampling device for monitoring the relative levels of two substances present in a biological system is also disclosed.

UR - https://worldwide.espacenet.com/publicationDetails/biblio?II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20091112&CC=US&NR=2009281405A1&KC=A1#

M3 - Patent

M1 - EP1401532 (WO03000340)

Y2 - 2002/06/17

ER -