Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

Michaela E Murphy; Akilavalli Narasimhan; Alexis Adrian; Ankur Kumar; Cara L Green; Carolina Soto-Palma; Chathurika Henpita; Christina Camell; Christopher S Morrow; Chung-Yang Yeh; Claire E Richardson; Cristal M Hill; Darcie L Moore; Dudley W Lamming; Eric R McGregor; Heather A Simmons; Heidi H Pak; Hua Bai; John M Denu; Josef Clark; Judith Simcox; Kishore Chittimalli; Korbyn Dahlquist; Kyoo-A Lee; Mariah Calubag; Mark Bouska; Matthew J Yousefzadeh; Michelle Sonsalla; Reji Babygirija; Rong Yuan; Tadataka Tsuji; Timothy Rhoads; Vinal Menon; Yagna Pr Jarajapu; Yun Zhu

doi:10.1007/s11357-021-00479-y

Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

Michaela E Murphy, Akilavalli Narasimhan, Alexis Adrian, Ankur Kumar, Cara L Green, Carolina Soto-Palma, Chathurika Henpita, Christina Camell, Christopher S Morrow, Chung-Yang Yeh, Claire E Richardson, Cristal M Hill, Darcie L Moore, Dudley W Lamming, Eric R McGregor, Heather A Simmons, Heidi H Pak, Hua Bai, John M Denu, Josef ClarkJudith Simcox, Kishore Chittimalli, Korbyn Dahlquist, Kyoo-A Lee, Mariah Calubag, Mark Bouska, Matthew J Yousefzadeh, Michelle Sonsalla, Reji Babygirija, Rong Yuan, Tadataka Tsuji, Timothy Rhoads, Vinal Menon, Yagna Pr Jarajapu, Yun Zhu

Department for Health

Research output: Contribution to journal › Article

3 Citations (SciVal)

Abstract

As the aging population on a global and national scale reaches ever increasing highs, research is essential to reduce the burden of aging and age-related diseases. Due to the complexity of aging, geroscience research necessarily spans a variety of disciplines and requires a collaborative and interdisciplinary approach. In order to leverage the respective strengths of different programs, centers, and institutes of aging across the Midwestern region to accelerate basic and translational geroscience, and to provide a strong training environment for postdoctoral fellows and graduate students, the Midwest Aging Consortium (MAC; https://midwestagingconsortium.org/) was organized in 2019, with an in-person symposium in 2019 and a virtual symposium in 2021 [1]. The MAC now spans 7 states in the Midwestern United States, and includes the Mayo Clinic; the Universities of Wisconsin–Madison, Minnesota, Iowa, Northwestern, and North Dakota; Iowa State University; Southern Illinois University; Indiana University-Bloomington; and The Ohio State University.

Many members of the MAC as well as other aging experts convened at the 2021 Annual Meeting of the American Aging Association in Madison, WI, home to the University of Wisconsin-Madison. Dr. Rozalyn Anderson, a MAC founder and the 2019–2021 AGE President, organized a spectacular event, with over 380 in person and virtual attendees; this article will summarize the science that members of MAC institutions presented at this meeting. The research presented can be broadly separated into a few main categories, including nutritional interventions, senescence and stem cells, metabolic homeostasis, and immunity.

Original language	English
Pages (from-to)	39-52
Number of pages	14
Journal	GeroScience
Volume	44
Issue number	1
Early online date	29 Oct 2021
DOIs	https://doi.org/10.1007/s11357-021-00479-y
Publication status	Published - 28 Feb 2022

Acknowledgements

We would like to thank Drs. Rozalyn Anderson, Paul Robbins, and Laura Nidernhofer for their role in the establishment of the MAC and their contributions
to this meeting as well as this report. In addition, we would like to thank the American Aging Association for organizing the meeting at which these talks were presented, and a special thanks to all sponsors of the 49th Annual AGE Metabolism of Aging Conference, including Gentech; School of Medicine and Public Health at University of Wisconsin-Madison; Geriatrics and Gerontology at University of Wisconsin-Madison; American Aging Association; American Federation for Aging Research; The Glenn Foundation for Medical Research; Morgridge Institute for Research; Orentreich Foundation for the Advancement of Science, Inc.; National Institutes of Health: National Institute on Aging; Healthy Aging & Longevity Research Institute; and Calico.

Funding

C.L.G. is supported by a Glenn/AFAR Foundation for Medical Research Postdoctoral Fellowship in Aging Research. M.J.Y. is supported by the Irene Diamond Fund/American Federation for Aging Research Postdoctoral Transition Award and in part by funds from the NIH/NIA (AG063543, AG059676, and AG056278 to Drs. Laura Niedernhofer and Paul Robbins). H.H.P. is supported by a NIA F31 predoctoral fellowship (NIA F31 AG066311). M.E.M. is supported by a Research Supplement to Promote Diversity in Health-Related Research (R01AG062328-03S1). C-Y.Y. is supported by the T32 Biology of Aging Program (T32 AG000213). D.W.L. and the Lamming laboratory are supported in part by research grants and funds from the National Institutes of Health (AG056771, AG062328 and DK125859) the University of Wisconsin-Madison School of Medicine and Public Health and Department of Medicine, and the U.S. Department of Veterans Affairs (I01-BX004031). T.W.R. is supported in part by funds from the NIH/NIA (AG070686 to TWR and AG057408 to Dr. Rozalyn Anderson) and the U.S. Department of Veterans Affiars (I01-BX003846 to Dr. Rozalyn Anderson). J.P.C. has received support from the T32 Biology of Aging Program (T32 AG000213). H.B., A.K., M.B., and the Bai laboratory is supported by NIH/NIA R01AG058741. J.M.D. is supported by GM059785, GM65386 and DK125859. C.S.M. has received support for this work by a NIH T32 T32GM008688, D.L.M. has received support for this work by an AFAR Young Investigator Award, a Sloan Foundation fellowship, and a DP2 NIH New Innovator Award. Y.P.R.J has received funding from NIGMS/NIA (AG056881). JS has received support from the NIH BIRCWH K12HD101368, start up funds from the Department of Biochemistry, and the NIH DRC P30DK020579. K.L. has received support from the T32 AG029796. V.M. has received support from NIH/NIA R01 AG063543, U19 AG056278, P01 AG062413, and Aligning Science across Parkinson’s ASAP-000592.Y.Z. and R.Y. are supported by William E. McElroy Charitable Foundation, NIA R21AG062985, ADA 1–19-IBS-126 and Research seed grant of Southern Illinois University School of Medicine. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. This work does not represent the views of the Department of Veterans Affairs or the United States Government.

Keywords

Geriatrics

Access to Document

10.1007/s11357-021-00479-y

Cite this

Murphy, M. E., Narasimhan, A., Adrian, A., Kumar, A., Green, C. L., Soto-Palma, C., Henpita, C., Camell, C., Morrow, C. S., Yeh, C.-Y., Richardson, C. E., Hill, C. M., Moore, D. L., Lamming, D. W., McGregor, E. R., Simmons, H. A., Pak, H. H., Bai, H., Denu, J. M., ... Zhu, Y. (2022). Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association. GeroScience, 44(1), 39-52. https://doi.org/10.1007/s11357-021-00479-y

Murphy, ME, Narasimhan, A, Adrian, A, Kumar, A, Green, CL, Soto-Palma, C, Henpita, C, Camell, C, Morrow, CS, Yeh, C-Y, Richardson, CE, Hill, CM, Moore, DL, Lamming, DW, McGregor, ER, Simmons, HA, Pak, HH, Bai, H, Denu, JM, Clark, J, Simcox, J, Chittimalli, K, Dahlquist, K, Lee, K-A, Calubag, M, Bouska, M, Yousefzadeh, MJ, Sonsalla, M, Babygirija, R, Yuan, R, Tsuji, T, Rhoads, T, Menon, V, Jarajapu, YP & Zhu, Y 2022, 'Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association', GeroScience, vol. 44, no. 1, pp. 39-52. https://doi.org/10.1007/s11357-021-00479-y

@article{69c402fbea524835a5b1dbe4cd6fc641,

title = "Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association",

abstract = "As the aging population on a global and national scale reaches ever increasing highs, research is essential to reduce the burden of aging and age-related diseases. Due to the complexity of aging, geroscience research necessarily spans a variety of disciplines and requires a collaborative and interdisciplinary approach. In order to leverage the respective strengths of different programs, centers, and institutes of aging across the Midwestern region to accelerate basic and translational geroscience, and to provide a strong training environment for postdoctoral fellows and graduate students, the Midwest Aging Consortium (MAC; https://midwestagingconsortium.org/) was organized in 2019, with an in-person symposium in 2019 and a virtual symposium in 2021 [1]. The MAC now spans 7 states in the Midwestern United States, and includes the Mayo Clinic; the Universities of Wisconsin–Madison, Minnesota, Iowa, Northwestern, and North Dakota; Iowa State University; Southern Illinois University; Indiana University-Bloomington; and The Ohio State University. Many members of the MAC as well as other aging experts convened at the 2021 Annual Meeting of the American Aging Association in Madison, WI, home to the University of Wisconsin-Madison. Dr. Rozalyn Anderson, a MAC founder and the 2019–2021 AGE President, organized a spectacular event, with over 380 in person and virtual attendees; this article will summarize the science that members of MAC institutions presented at this meeting. The research presented can be broadly separated into a few main categories, including nutritional interventions, senescence and stem cells, metabolic homeostasis, and immunity.",

keywords = "Geriatrics",

author = "Murphy, \{Michaela E\} and Akilavalli Narasimhan and Alexis Adrian and Ankur Kumar and Green, \{Cara L\} and Carolina Soto-Palma and Chathurika Henpita and Christina Camell and Morrow, \{Christopher S\} and Chung-Yang Yeh and Richardson, \{Claire E\} and Hill, \{Cristal M\} and Moore, \{Darcie L\} and Lamming, \{Dudley W\} and McGregor, \{Eric R\} and Simmons, \{Heather A\} and Pak, \{Heidi H\} and Hua Bai and Denu, \{John M\} and Josef Clark and Judith Simcox and Kishore Chittimalli and Korbyn Dahlquist and Kyoo-A Lee and Mariah Calubag and Mark Bouska and Yousefzadeh, \{Matthew J\} and Michelle Sonsalla and Reji Babygirija and Rong Yuan and Tadataka Tsuji and Timothy Rhoads and Vinal Menon and Jarajapu, \{Yagna Pr\} and Yun Zhu",

year = "2022",

month = feb,

day = "28",

doi = "10.1007/s11357-021-00479-y",

language = "English",

volume = "44",

pages = "39--52",

journal = "GeroScience",

issn = "2509-2715",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "1",

}

TY - JOUR

T1 - Metabolism in the Midwest

T2 - research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

AU - Murphy, Michaela E

AU - Narasimhan, Akilavalli

AU - Adrian, Alexis

AU - Kumar, Ankur

AU - Green, Cara L

AU - Soto-Palma, Carolina

AU - Henpita, Chathurika

AU - Camell, Christina

AU - Morrow, Christopher S

AU - Yeh, Chung-Yang

AU - Richardson, Claire E

AU - Hill, Cristal M

AU - Moore, Darcie L

AU - Lamming, Dudley W

AU - McGregor, Eric R

AU - Simmons, Heather A

AU - Pak, Heidi H

AU - Bai, Hua

AU - Denu, John M

AU - Clark, Josef

AU - Simcox, Judith

AU - Chittimalli, Kishore

AU - Dahlquist, Korbyn

AU - Lee, Kyoo-A

AU - Calubag, Mariah

AU - Bouska, Mark

AU - Yousefzadeh, Matthew J

AU - Sonsalla, Michelle

AU - Babygirija, Reji

AU - Yuan, Rong

AU - Tsuji, Tadataka

AU - Rhoads, Timothy

AU - Menon, Vinal

AU - Jarajapu, Yagna Pr

AU - Zhu, Yun

PY - 2022/2/28

Y1 - 2022/2/28

N2 - As the aging population on a global and national scale reaches ever increasing highs, research is essential to reduce the burden of aging and age-related diseases. Due to the complexity of aging, geroscience research necessarily spans a variety of disciplines and requires a collaborative and interdisciplinary approach. In order to leverage the respective strengths of different programs, centers, and institutes of aging across the Midwestern region to accelerate basic and translational geroscience, and to provide a strong training environment for postdoctoral fellows and graduate students, the Midwest Aging Consortium (MAC; https://midwestagingconsortium.org/) was organized in 2019, with an in-person symposium in 2019 and a virtual symposium in 2021 [1]. The MAC now spans 7 states in the Midwestern United States, and includes the Mayo Clinic; the Universities of Wisconsin–Madison, Minnesota, Iowa, Northwestern, and North Dakota; Iowa State University; Southern Illinois University; Indiana University-Bloomington; and The Ohio State University. Many members of the MAC as well as other aging experts convened at the 2021 Annual Meeting of the American Aging Association in Madison, WI, home to the University of Wisconsin-Madison. Dr. Rozalyn Anderson, a MAC founder and the 2019–2021 AGE President, organized a spectacular event, with over 380 in person and virtual attendees; this article will summarize the science that members of MAC institutions presented at this meeting. The research presented can be broadly separated into a few main categories, including nutritional interventions, senescence and stem cells, metabolic homeostasis, and immunity.

AB - As the aging population on a global and national scale reaches ever increasing highs, research is essential to reduce the burden of aging and age-related diseases. Due to the complexity of aging, geroscience research necessarily spans a variety of disciplines and requires a collaborative and interdisciplinary approach. In order to leverage the respective strengths of different programs, centers, and institutes of aging across the Midwestern region to accelerate basic and translational geroscience, and to provide a strong training environment for postdoctoral fellows and graduate students, the Midwest Aging Consortium (MAC; https://midwestagingconsortium.org/) was organized in 2019, with an in-person symposium in 2019 and a virtual symposium in 2021 [1]. The MAC now spans 7 states in the Midwestern United States, and includes the Mayo Clinic; the Universities of Wisconsin–Madison, Minnesota, Iowa, Northwestern, and North Dakota; Iowa State University; Southern Illinois University; Indiana University-Bloomington; and The Ohio State University. Many members of the MAC as well as other aging experts convened at the 2021 Annual Meeting of the American Aging Association in Madison, WI, home to the University of Wisconsin-Madison. Dr. Rozalyn Anderson, a MAC founder and the 2019–2021 AGE President, organized a spectacular event, with over 380 in person and virtual attendees; this article will summarize the science that members of MAC institutions presented at this meeting. The research presented can be broadly separated into a few main categories, including nutritional interventions, senescence and stem cells, metabolic homeostasis, and immunity.

KW - Geriatrics

U2 - 10.1007/s11357-021-00479-y

DO - 10.1007/s11357-021-00479-y

M3 - Article

C2 - 34714522

SN - 2509-2715

VL - 44

SP - 39

EP - 52

JO - GeroScience

JF - GeroScience

IS - 1

ER -

Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association

Abstract

Acknowledgements

Funding

Keywords

Access to Document

Fingerprint

Cite this