Mathematical models for a G0 phase in Saccharomyces cerevisiae

N F Britton, A E Wheals

Research output: Contribution to journalArticle

Abstract

Three models for the cell cycle of the budding yeast, Saccharomyces cerevisiae, which include a reversible G0 phase during proliferation, are presented. The analysis gives estimates for various quantities of biological interest, such as the probability of entry to and rate of exit from the G0 phase, the average duration of a cell in the G0 phase, the cycle time of cycling daughters and the population doubling time of cycling cells, none of which is easily measurable.

Original languageEnglish
Pages (from-to)269-281
Number of pages13
JournalJournal of Theoretical Biology
Volume125
Issue number3
Publication statusPublished - 7 Apr 1987

Fingerprint

Cell Cycle Resting Phase
Saccharomyces Cerevisiae
interphase
Yeast
Saccharomyces cerevisiae
Theoretical Models
mathematical models
Cycling
Mathematical Model
Mathematical models
Saccharomycetales
Cell
Cells
Cell Cycle
Doubling
Proliferation
cell cycle
cells
yeasts
duration

Keywords

  • Cell Cycle
  • Cell Division
  • Interphase
  • Mathematics
  • Models, Biological
  • Saccharomyces cerevisiae

Cite this

Mathematical models for a G0 phase in Saccharomyces cerevisiae. / Britton, N F; Wheals, A E.

In: Journal of Theoretical Biology, Vol. 125, No. 3, 07.04.1987, p. 269-281.

Research output: Contribution to journalArticle

@article{1ed7906194734a8badff33426e4b23bf,
title = "Mathematical models for a G0 phase in Saccharomyces cerevisiae",
abstract = "Three models for the cell cycle of the budding yeast, Saccharomyces cerevisiae, which include a reversible G0 phase during proliferation, are presented. The analysis gives estimates for various quantities of biological interest, such as the probability of entry to and rate of exit from the G0 phase, the average duration of a cell in the G0 phase, the cycle time of cycling daughters and the population doubling time of cycling cells, none of which is easily measurable.",
keywords = "Cell Cycle, Cell Division, Interphase, Mathematics, Models, Biological, Saccharomyces cerevisiae",
author = "Britton, {N F} and Wheals, {A E}",
year = "1987",
month = "4",
day = "7",
language = "English",
volume = "125",
pages = "269--281",
journal = "Journal of Theoretical Biology",
issn = "0022-5193",
publisher = "Elsevier Academic Press Inc",
number = "3",

}

TY - JOUR

T1 - Mathematical models for a G0 phase in Saccharomyces cerevisiae

AU - Britton, N F

AU - Wheals, A E

PY - 1987/4/7

Y1 - 1987/4/7

N2 - Three models for the cell cycle of the budding yeast, Saccharomyces cerevisiae, which include a reversible G0 phase during proliferation, are presented. The analysis gives estimates for various quantities of biological interest, such as the probability of entry to and rate of exit from the G0 phase, the average duration of a cell in the G0 phase, the cycle time of cycling daughters and the population doubling time of cycling cells, none of which is easily measurable.

AB - Three models for the cell cycle of the budding yeast, Saccharomyces cerevisiae, which include a reversible G0 phase during proliferation, are presented. The analysis gives estimates for various quantities of biological interest, such as the probability of entry to and rate of exit from the G0 phase, the average duration of a cell in the G0 phase, the cycle time of cycling daughters and the population doubling time of cycling cells, none of which is easily measurable.

KW - Cell Cycle

KW - Cell Division

KW - Interphase

KW - Mathematics

KW - Models, Biological

KW - Saccharomyces cerevisiae

M3 - Article

VL - 125

SP - 269

EP - 281

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

IS - 3

ER -