Mathematical models for a G0 phase in Saccharomyces cerevisiae

Three models for the cell cycle of the budding yeast, Saccharomyces cerevisiae, which include a reversible G0 phase during proliferation, are presented. The analysis gives estimates for various quantities of biological interest, such as the probability of entry to and rate of exit from the G0 phase, the average duration of a cell in the G0 phase, the cycle time of cycling daughters and the population doubling time of cycling cells, none of which is easily measurable.