Materials and Methods Relating to Glycosylation

Andrew Watts; Amanda Mackenzie; Terrence Kantner

Materials and Methods Relating to Glycosylation

Andrew Watts (Inventor), Amanda Mackenzie (Inventor), Terrence Kantner (Inventor)

Department of Life Sciences

Research output: Patent

Abstract

Techniques to glycosylation are described, and more particularly to the production of glycosylation structures that are resistant to enzymatic degradation, thereby modulating one or more of their biological properties or those of therapeutic moieties incorporating them, and in particular to reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to produce covalent conjugates of the sugar acceptor and one or more of the sialic acid compounds.

Original language	English
Patent number	CA2768155 (A1)
IPC	A61K47/48
Publication status	Published - 23 Dec 2010

Cite this

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title = "Materials and Methods Relating to Glycosylation",

abstract = "Techniques to glycosylation are described, and more particularly to the production of glycosylation structures that are resistant to enzymatic degradation, thereby modulating one or more of their biological properties or those of therapeutic moieties incorporating them, and in particular to reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to produce covalent conjugates of the sugar acceptor and one or more of the sialic acid compounds.",

author = "Andrew Watts and Amanda Mackenzie and Terrence Kantner",

year = "2010",

month = dec,

day = "23",

language = "English",

type = "Patent",

note = "CA2768155 (A1); A61K47/48",

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TY - PAT

T1 - Materials and Methods Relating to Glycosylation

AU - Watts, Andrew

AU - Mackenzie, Amanda

AU - Kantner, Terrence

PY - 2010/12/23

Y1 - 2010/12/23

N2 - Techniques to glycosylation are described, and more particularly to the production of glycosylation structures that are resistant to enzymatic degradation, thereby modulating one or more of their biological properties or those of therapeutic moieties incorporating them, and in particular to reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to produce covalent conjugates of the sugar acceptor and one or more of the sialic acid compounds.

AB - Techniques to glycosylation are described, and more particularly to the production of glycosylation structures that are resistant to enzymatic degradation, thereby modulating one or more of their biological properties or those of therapeutic moieties incorporating them, and in particular to reacting activated carbohydrate substrates containing fluorine, such as 3-fluoro sialic acid compounds, with sugar acceptors to produce covalent conjugates of the sugar acceptor and one or more of the sialic acid compounds.

M3 - Patent

M1 - CA2768155 (A1)

ER -

Materials and Methods Relating to Glycosylation

Abstract

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