Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Ri Ming Huang, Yin Ning Chen, Ziyu Zeng, Cheng Hai Gao, Xiangdong Su, Yan Peng

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.

Original languageEnglish
Pages (from-to)5817-5838
Number of pages22
JournalMarine Drugs
Volume12
Issue number12
DOIs
Publication statusPublished - 2 Dec 2014

Keywords

  • Biological activity
  • Biosynthetic pathway
  • Marine organism
  • Nucleoside
  • Synthesis

ASJC Scopus subject areas

  • Drug Discovery

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    Huang, R. M., Chen, Y. N., Zeng, Z., Gao, C. H., Su, X., & Peng, Y. (2014). Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis. Marine Drugs, 12(12), 5817-5838. https://doi.org/10.3390/md12125817