Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Ri Ming Huang; Yin Ning Chen; Ziyu Zeng; Cheng Hai Gao; Xiangdong Su; Yan Peng

doi:10.3390/md12125817

Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Ri Ming Huang, Yin Ning Chen, Ziyu Zeng, Cheng Hai Gao, Xiangdong Su, Yan Peng

Research output: Contribution to journal › Review article › peer-review

44 Citations (SciVal)

Abstract

Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.

Original language	English
Pages (from-to)	5817-5838
Number of pages	22
Journal	Marine Drugs
Volume	12
Issue number	12
DOIs	https://doi.org/10.3390/md12125817
Publication status	Published - 2 Dec 2014

Keywords

Biological activity
Biosynthetic pathway
Marine organism
Nucleoside
Synthesis

ASJC Scopus subject areas

Drug Discovery

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/md12125817Licence: CC BY

Cite this

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title = "Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis",

abstract = "Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.",

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T1 - Marine nucleosides

T2 - Structure, bioactivity, synthesis and biosynthesis

AU - Huang, Ri Ming

AU - Chen, Yin Ning

AU - Zeng, Ziyu

AU - Gao, Cheng Hai

AU - Su, Xiangdong

AU - Peng, Yan

PY - 2014/12/2

Y1 - 2014/12/2

N2 - Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.

AB - Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.

KW - Biological activity

KW - Biosynthetic pathway

KW - Marine organism

KW - Nucleoside

KW - Synthesis

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UR - https://doi.org/10.3390/md12125817

U2 - 10.3390/md12125817

DO - 10.3390/md12125817

M3 - Review article

AN - SCOPUS:84919905432

SN - 1660-3397

VL - 12

SP - 5817

EP - 5838

JO - Marine Drugs

JF - Marine Drugs

IS - 12

ER -

Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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