TY - JOUR
T1 - Long-time solution of the equations describing the flow of 22Na+ in a finite composite system containing a synthetic phospholipid-protein membrane
T2 - Calculation of permeability coefficient
AU - Guy, Richard H.
AU - Fleming, Robert
PY - 1980/1
Y1 - 1980/1
N2 - Flow equations are developed using Laplace transform theory to describe the diffusion of 22Na+ through a composite system consisting of a protein solution and a phospholipid sol with a membrane at the interface. An approximation, valid at long times (t > 1.5 × 105 s), is then introduced enabling calculation of an unambiguous limiting value for the permeability coefficient of the membrane.
AB - Flow equations are developed using Laplace transform theory to describe the diffusion of 22Na+ through a composite system consisting of a protein solution and a phospholipid sol with a membrane at the interface. An approximation, valid at long times (t > 1.5 × 105 s), is then introduced enabling calculation of an unambiguous limiting value for the permeability coefficient of the membrane.
UR - http://www.scopus.com/inward/record.url?scp=49149147991&partnerID=8YFLogxK
U2 - 10.1016/0378-5173(80)90139-8
DO - 10.1016/0378-5173(80)90139-8
M3 - Article
AN - SCOPUS:49149147991
SN - 0378-5173
VL - 4
SP - 241
EP - 248
JO - International Journal of Pharmaceutics
JF - International Journal of Pharmaceutics
IS - 3
ER -