Loganin-type iridoids as chemotaxonomic markers in Glandularia gooddingii (Briq.) Solbrig

Mai A.M. Ahmed; Nesma M. Mohamed; Timothy J. Woodman; Gabriele Kociok-Köhn; Ian S. Blagbrough

doi:10.1016/j.phytol.2021.04.003

Loganin-type iridoids as chemotaxonomic markers in Glandularia gooddingii (Briq.) Solbrig

Mai A.M. Ahmed, Nesma M. Mohamed, Timothy J. Woodman, Gabriele Kociok-Köhn, Ian S. Blagbrough

Assiut University

Research output: Contribution to journal › Article › peer-review

3 Citations (SciVal)

Abstract

Glandularia is one of the genera that has few published phytochemical studies and, for many years, it was considered to be within the genus Verbena. Verbena is known to be rich in iridoids, flavonoids, and phenylpropanoids. Three iridoid glucosides, 6β-hydroxyipolamiide, phlomiol, and pulchelloside I (3-5) were isolated from the methanolic extract of the whole plant of Glandularia gooddingii (Briq.) Solbrig and elucidated by extensive analysis of the 1D- and 2D-NMR as well as by HR-ESI-QTOF mass spectra. Identification of these iridoids and determining their chemical nature supports the chemotaxonomic classification of the genus Glandularia and defines certain members belonging to it. This is the first report of the X-ray crystal structure of 6β-hydroxyipolamiide (3).

Original language	English
Pages (from-to)	68-73
Number of pages	6
Journal	Phytochemistry Letters
Volume	44
Early online date	2 Jun 2021
DOIs	https://doi.org/10.1016/j.phytol.2021.04.003
Publication status	Published - 31 Aug 2021

Bibliographical note

Funding Information:
We thank the Egyptian Government for financial support to M.A.M.A. NMR and MS equipment and the X-ray diffractometer were provided by the Material and Chemical Characterization Facility at the University of Bath.

Keywords

6β-Hydroxyipolamiide
Chemotaxonomic marker
Glandularia gooddingii (Briq.) Solbrig
Verbenaceae
X-ray crystallography

ASJC Scopus subject areas

Biotechnology
Biochemistry
Agronomy and Crop Science
Plant Science

Access to Document

10.1016/j.phytol.2021.04.003

Cite this

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title = "Loganin-type iridoids as chemotaxonomic markers in Glandularia gooddingii (Briq.) Solbrig",

abstract = "Glandularia is one of the genera that has few published phytochemical studies and, for many years, it was considered to be within the genus Verbena. Verbena is known to be rich in iridoids, flavonoids, and phenylpropanoids. Three iridoid glucosides, 6β-hydroxyipolamiide, phlomiol, and pulchelloside I (3-5) were isolated from the methanolic extract of the whole plant of Glandularia gooddingii (Briq.) Solbrig and elucidated by extensive analysis of the 1D- and 2D-NMR as well as by HR-ESI-QTOF mass spectra. Identification of these iridoids and determining their chemical nature supports the chemotaxonomic classification of the genus Glandularia and defines certain members belonging to it. This is the first report of the X-ray crystal structure of 6β-hydroxyipolamiide (3).",

keywords = "6β-Hydroxyipolamiide, Chemotaxonomic marker, Glandularia gooddingii (Briq.) Solbrig, Verbenaceae, X-ray crystallography",

author = "Ahmed, {Mai A.M.} and Mohamed, {Nesma M.} and Woodman, {Timothy J.} and Gabriele Kociok-K{\"o}hn and Blagbrough, {Ian S.}",

note = "Funding Information: We thank the Egyptian Government for financial support to M.A.M.A. NMR and MS equipment and the X-ray diffractometer were provided by the Material and Chemical Characterization Facility at the University of Bath. ",

year = "2021",

month = aug,

day = "31",

doi = "10.1016/j.phytol.2021.04.003",

language = "English",

volume = "44",

pages = "68--73",

journal = "Phytochemistry Letters",

issn = "1874-3900",

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TY - JOUR

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AU - Ahmed, Mai A.M.

AU - Mohamed, Nesma M.

AU - Woodman, Timothy J.

AU - Kociok-Köhn, Gabriele

AU - Blagbrough, Ian S.

N1 - Funding Information: We thank the Egyptian Government for financial support to M.A.M.A. NMR and MS equipment and the X-ray diffractometer were provided by the Material and Chemical Characterization Facility at the University of Bath.

PY - 2021/8/31

Y1 - 2021/8/31

N2 - Glandularia is one of the genera that has few published phytochemical studies and, for many years, it was considered to be within the genus Verbena. Verbena is known to be rich in iridoids, flavonoids, and phenylpropanoids. Three iridoid glucosides, 6β-hydroxyipolamiide, phlomiol, and pulchelloside I (3-5) were isolated from the methanolic extract of the whole plant of Glandularia gooddingii (Briq.) Solbrig and elucidated by extensive analysis of the 1D- and 2D-NMR as well as by HR-ESI-QTOF mass spectra. Identification of these iridoids and determining their chemical nature supports the chemotaxonomic classification of the genus Glandularia and defines certain members belonging to it. This is the first report of the X-ray crystal structure of 6β-hydroxyipolamiide (3).

AB - Glandularia is one of the genera that has few published phytochemical studies and, for many years, it was considered to be within the genus Verbena. Verbena is known to be rich in iridoids, flavonoids, and phenylpropanoids. Three iridoid glucosides, 6β-hydroxyipolamiide, phlomiol, and pulchelloside I (3-5) were isolated from the methanolic extract of the whole plant of Glandularia gooddingii (Briq.) Solbrig and elucidated by extensive analysis of the 1D- and 2D-NMR as well as by HR-ESI-QTOF mass spectra. Identification of these iridoids and determining their chemical nature supports the chemotaxonomic classification of the genus Glandularia and defines certain members belonging to it. This is the first report of the X-ray crystal structure of 6β-hydroxyipolamiide (3).

KW - 6β-Hydroxyipolamiide

KW - Chemotaxonomic marker

KW - Glandularia gooddingii (Briq.) Solbrig

KW - Verbenaceae

KW - X-ray crystallography

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DO - 10.1016/j.phytol.2021.04.003

M3 - Article

AN - SCOPUS:85107155061

SN - 1874-3900

VL - 44

SP - 68

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JO - Phytochemistry Letters

JF - Phytochemistry Letters

ER -

Loganin-type iridoids as chemotaxonomic markers in Glandularia gooddingii (Briq.) Solbrig

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Avance NEO 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer (1South)

Dual source (Cu and Mo) Single Crystal Diffractometer (SuperNova)

Electrospray Time-of-Flight Mass Spectrometer (Open-Access)

Cite this

Loganin-type iridoids as chemotaxonomic markers in Glandularia gooddingii (Briq.) Solbrig

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Equipment

Avance NEO 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer (1South)

Dual source (Cu and Mo) Single Crystal Diffractometer (SuperNova)

Electrospray Time-of-Flight Mass Spectrometer (Open-Access)

Cite this