Leukocyte deformation in cardiac assist devices

Katharine Fraser, Ina Laura Pieper

Research output: Contribution to conferencePaperpeer-review

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Ventricular Assist Devices (VADs) are pumps which support failing hearts. While considered by some surgeons as gold standard treatment, current VADs have many complications related to the imposed stress on the blood. In particular, damage to the leukocytes may contribute to infections, currently the biggest post-surgical problem. Our aim was to create a numerical model of a leukocyte
which can be used to investigate leukocyte deformation in VADs. The leukocyte was modelled as a compound liquid droplet and solved in OpenFOAM using the multiphaseInterfoam solver. Initial results are presented for different shear rates, extensional versus planar shear, and for different nucleus sizes.
Original languageEnglish
Number of pages445
Publication statusPublished - 10 Apr 2017
EventComputational and Mathematical Biomedical Engineering - University of Pittsburgh, Pittsburgh, USA United States
Duration: 10 Apr 201712 Apr 2017
Conference number: 5


ConferenceComputational and Mathematical Biomedical Engineering
Abbreviated titleCMBE 2017
Country/TerritoryUSA United States
Internet address


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