Iridium-catalyzed formylation of amines with paraformaldehyde

Ourida Saidi, M J Bamford, A J Blacker, James Lynch, S P Marsden, Pawel Plucinski, R J Watson, Jonathan M J Williams

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47 Citations (Scopus)


Amines have been formylated using aqueous formaldehyde or paraformaldehyde and the iridium catalyst [Cp*IrI2](2). Paraformaldehyde acts as both a formylating agent and an oxidant.
Original languageEnglish
Pages (from-to)5804-5806
Number of pages3
JournalTetrahedron Letters
Issue number44
Publication statusPublished - 3 Nov 2010

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    Saidi, O., Bamford, M. J., Blacker, A. J., Lynch, J., Marsden, S. P., Plucinski, P., Watson, R. J., & Williams, J. M. J. (2010). Iridium-catalyzed formylation of amines with paraformaldehyde. Tetrahedron Letters, 51(44), 5804-5806.