Abstract
The Ireland-Claisen [3,3]-sigmatropic rearrangement of an allylic glycinate bearing a remote chiral enol ether has been studied. Remote exopericyclic stereocontrol is achievable in this instance. The product from this rearrangement has been progressed through a formal total synthesis of the natural antibiotic, furanomycin.
Original language | English |
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Pages (from-to) | 6027-6029 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 52 |
Issue number | 45 |
DOIs | |
Publication status | Published - 9 Nov 2011 |
Keywords
- sigmatropic
- amino acid
- furanomycin
- rearrangement
- Ireland-Claisen