Ion-selective lipid bilayers tethered to microcontact printed self-assembled monolayers containing cholesterol derivatives

A. Toby, A. Jenkins, Richard J. Bushby, Neville Boden, Stephen D. Evans, Peter F. Knowles, Quanying Liu, Robert E. Miles, Simon D. Ogier

Research output: Contribution to journalArticlepeer-review

70 Citations (SciVal)

Abstract

Microcontact printing has been used to prepare patterned self-assembled monolayers (SAMs) of cholesterylpolyethylenoxythiol. These patterned SAMs were used as supports for the formation of integral supported lipid bilayers. Biofunctionality was confirmed by addition of valinomycin ionophores and gramicidin ion channels. Impedance spectroscopy of the resulting bilayer structures, incorporating valinomycin and the gramicidin, showed the expected ion selectivity.

Original languageEnglish
Pages (from-to)4675-4678
Number of pages4
JournalLangmuir
Volume14
Issue number17
DOIs
Publication statusPublished - 1 Jan 1998

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

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