Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids)

Lingling Zhang, Yunhong Jiang, Yulong Ding, Malcolm Povey, David W York

Research output: Contribution to journalArticle

705 Citations (Scopus)

Abstract

The antibacterial behaviour of suspensions of zinc oxide nanoparticles (ZnO nanofluids) against E. Coli has been investigated. ZnO nanoparticles from two sources are used to formulate nanofluids. The effects of particle size, concentration and the use of dispersants on the antibacterial behaviour are examined. The results show that the ZnO nanofluids have bacteriostatic activity against E. coli. The antibacterial activity increases with increasing nanoparticle concentration and increases with decreasing particle size. Particle concentration is observed to be more important than particle size under the conditions of this work. The results also show that the use of two types of dispersants (Polyethylene Glycol (PEG) and Polyvinylpyrolidone (PVP)) does not affect much the antibacterial activity of ZnO nanofluids but enhances the stability of the suspensions. SEM analyses of the bacteria before and after treatment with ZnO nanofluids show that the presence of ZnO nanoparticles damages the membrane wall of the bacteria. Electrochemical measurements using a model DOPC monolayer suggest some direct interaction between ZnO nanoparticles and the bacteria membrane at high ZnO concentrations.

LanguageEnglish
Pages479-489
Number of pages11
JournalJournal of Nanoparticle Research
Volume9
Issue number3
DOIs
StatusPublished - Jun 2007

Fingerprint

Nanofluid
Nanoparticles
Suspensions
nanoparticles
bacteria
Bacteria
Particle size
Escherichia coli
Particle Size
membranes
Zinc Oxide
Membranes
Escherichia Coli
Zinc oxide
zinc oxides
Polyethylene glycols
Membrane
glycols
polyethylenes
Monolayers

Keywords

  • Antibacterial activity
  • E. coli
  • Mechanisms
  • Nanoengineering
  • Nanofluids
  • Zinc oxide nanoparticles

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Atomic and Molecular Physics, and Optics
  • Modelling and Simulation
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids). / Zhang, Lingling; Jiang, Yunhong; Ding, Yulong; Povey, Malcolm; York, David W.

In: Journal of Nanoparticle Research, Vol. 9, No. 3, 06.2007, p. 479-489.

Research output: Contribution to journalArticle

Zhang, Lingling ; Jiang, Yunhong ; Ding, Yulong ; Povey, Malcolm ; York, David W. / Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids). In: Journal of Nanoparticle Research. 2007 ; Vol. 9, No. 3. pp. 479-489.
@article{f0e38cb932774ab289571cd3795a878d,
title = "Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids)",
abstract = "The antibacterial behaviour of suspensions of zinc oxide nanoparticles (ZnO nanofluids) against E. Coli has been investigated. ZnO nanoparticles from two sources are used to formulate nanofluids. The effects of particle size, concentration and the use of dispersants on the antibacterial behaviour are examined. The results show that the ZnO nanofluids have bacteriostatic activity against E. coli. The antibacterial activity increases with increasing nanoparticle concentration and increases with decreasing particle size. Particle concentration is observed to be more important than particle size under the conditions of this work. The results also show that the use of two types of dispersants (Polyethylene Glycol (PEG) and Polyvinylpyrolidone (PVP)) does not affect much the antibacterial activity of ZnO nanofluids but enhances the stability of the suspensions. SEM analyses of the bacteria before and after treatment with ZnO nanofluids show that the presence of ZnO nanoparticles damages the membrane wall of the bacteria. Electrochemical measurements using a model DOPC monolayer suggest some direct interaction between ZnO nanoparticles and the bacteria membrane at high ZnO concentrations.",
keywords = "Antibacterial activity, E. coli, Mechanisms, Nanoengineering, Nanofluids, Zinc oxide nanoparticles",
author = "Lingling Zhang and Yunhong Jiang and Yulong Ding and Malcolm Povey and York, {David W}",
year = "2007",
month = "6",
doi = "10.1007/s11051-006-9150-1",
language = "English",
volume = "9",
pages = "479--489",
journal = "Journal of Nanoparticle Research",
issn = "1388-0764",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids)

AU - Zhang, Lingling

AU - Jiang, Yunhong

AU - Ding, Yulong

AU - Povey, Malcolm

AU - York, David W

PY - 2007/6

Y1 - 2007/6

N2 - The antibacterial behaviour of suspensions of zinc oxide nanoparticles (ZnO nanofluids) against E. Coli has been investigated. ZnO nanoparticles from two sources are used to formulate nanofluids. The effects of particle size, concentration and the use of dispersants on the antibacterial behaviour are examined. The results show that the ZnO nanofluids have bacteriostatic activity against E. coli. The antibacterial activity increases with increasing nanoparticle concentration and increases with decreasing particle size. Particle concentration is observed to be more important than particle size under the conditions of this work. The results also show that the use of two types of dispersants (Polyethylene Glycol (PEG) and Polyvinylpyrolidone (PVP)) does not affect much the antibacterial activity of ZnO nanofluids but enhances the stability of the suspensions. SEM analyses of the bacteria before and after treatment with ZnO nanofluids show that the presence of ZnO nanoparticles damages the membrane wall of the bacteria. Electrochemical measurements using a model DOPC monolayer suggest some direct interaction between ZnO nanoparticles and the bacteria membrane at high ZnO concentrations.

AB - The antibacterial behaviour of suspensions of zinc oxide nanoparticles (ZnO nanofluids) against E. Coli has been investigated. ZnO nanoparticles from two sources are used to formulate nanofluids. The effects of particle size, concentration and the use of dispersants on the antibacterial behaviour are examined. The results show that the ZnO nanofluids have bacteriostatic activity against E. coli. The antibacterial activity increases with increasing nanoparticle concentration and increases with decreasing particle size. Particle concentration is observed to be more important than particle size under the conditions of this work. The results also show that the use of two types of dispersants (Polyethylene Glycol (PEG) and Polyvinylpyrolidone (PVP)) does not affect much the antibacterial activity of ZnO nanofluids but enhances the stability of the suspensions. SEM analyses of the bacteria before and after treatment with ZnO nanofluids show that the presence of ZnO nanoparticles damages the membrane wall of the bacteria. Electrochemical measurements using a model DOPC monolayer suggest some direct interaction between ZnO nanoparticles and the bacteria membrane at high ZnO concentrations.

KW - Antibacterial activity

KW - E. coli

KW - Mechanisms

KW - Nanoengineering

KW - Nanofluids

KW - Zinc oxide nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=34248343855&partnerID=8YFLogxK

U2 - 10.1007/s11051-006-9150-1

DO - 10.1007/s11051-006-9150-1

M3 - Article

VL - 9

SP - 479

EP - 489

JO - Journal of Nanoparticle Research

T2 - Journal of Nanoparticle Research

JF - Journal of Nanoparticle Research

SN - 1388-0764

IS - 3

ER -