Investigating Sex Differences in Emotion Recognition, Learning, and Regulation among Youths with Conduct Disorder

Gregor Kohls, Sarah Baumann, Malou Gundlach, Wolfgang Scharke, Anka Bernhard, Anne Martinelli, Katharina Ackermann, Linda Kersten, Martin Prätzlich, Helena Oldenhof, Lucres Jansen, Lisette van den Boogaard, Areti Smaragdi, Karen Gonzalez-Madruga, Harriet Cornwell, Jack Rogers, Ruth Pauli, Roberta Clanton, Rosalind Baker, Aitana Bigorra GualbaBeate Herpertz-Dahlmann, Aranzazu Fernández-Rivas, Arne Popma, Christina Stadler, Stephane De Brito, James Blair, Christine M. Freitag, Graeme Fairchild, Kerstin Konrad

Research output: Contribution to journalArticle

Abstract

Objective: Conduct disorder (CD) is a serious neurodevelopmental disorder marked by notably higher prevalence rates for boys than girls. Converging evidence suggests that CD is associated with impairments in emotion recognition, learning, and regulation. However, it is not known whether there are sex differences in the relationship between CD and emotion dysfunction. Prior studies on emotion functioning in CD have so far been underpowered for investigating sex differences. Therefore, our primary aim was to characterize emotion processing skills in a large sample of girls and boys with CD compared to typically developing controls (TDCs) using a comprehensive neuropsychological test battery. Method: We included 542 youths with CD (317 girls) and 710 TDCs (479 girls), 9 to 18 years of age, from a European multisite study (FemNAT-CD). Participants completed three experimental tasks assessing emotion recognition, learning, and regulation, respectively. Data were analyzed to test for effects of group and sex, and group-by-sex interactions, while controlling for potentially confounding factors. Results: Relative to TDCs, youths with CD showed impaired emotion recognition (that was related to more physical and proactive aggression, and higher CU traits), emotional learning (specifically from punishment), and emotion regulation. Boys and girls with CD, however, displayed similar impairments in emotion processing. Conclusion: This study provides compelling evidence for a relationship between CD and deficient neurocognitive functioning across three emotional domains that have previously been linked to CD etiology. However, there was no support for sex-specific profiles of emotion dysfunction, suggesting that current neurocognitive models of CD apply equally to both sexes.

Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Early online date23 Apr 2019
DOIs
Publication statusE-pub ahead of print - 23 Apr 2019

Keywords

  • FemNAT-CD
  • callous-unemotional traits
  • conduct disorder
  • emotion processing
  • sex differences

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

Cite this

Investigating Sex Differences in Emotion Recognition, Learning, and Regulation among Youths with Conduct Disorder. / Kohls, Gregor; Baumann, Sarah ; Gundlach, Malou ; Scharke, Wolfgang; Bernhard, Anka; Martinelli, Anne; Ackermann, Katharina ; Kersten, Linda; Prätzlich, Martin; Oldenhof, Helena ; Jansen, Lucres; van den Boogaard, Lisette; Smaragdi, Areti; Gonzalez-Madruga, Karen; Cornwell, Harriet; Rogers, Jack; Pauli, Ruth ; Clanton, Roberta; Baker, Rosalind; Bigorra Gualba, Aitana ; Herpertz-Dahlmann, Beate ; Fernández-Rivas, Aranzazu ; Popma, Arne; Stadler, Christina; De Brito, Stephane; Blair, James; Freitag, Christine M.; Fairchild, Graeme; Konrad, Kerstin.

In: Journal of the American Academy of Child and Adolescent Psychiatry, 23.04.2019, p. 1-12.

Research output: Contribution to journalArticle

Kohls, G, Baumann, S, Gundlach, M, Scharke, W, Bernhard, A, Martinelli, A, Ackermann, K, Kersten, L, Prätzlich, M, Oldenhof, H, Jansen, L, van den Boogaard, L, Smaragdi, A, Gonzalez-Madruga, K, Cornwell, H, Rogers, J, Pauli, R, Clanton, R, Baker, R, Bigorra Gualba, A, Herpertz-Dahlmann, B, Fernández-Rivas, A, Popma, A, Stadler, C, De Brito, S, Blair, J, Freitag, CM, Fairchild, G & Konrad, K 2019, 'Investigating Sex Differences in Emotion Recognition, Learning, and Regulation among Youths with Conduct Disorder', Journal of the American Academy of Child and Adolescent Psychiatry, pp. 1-12. https://doi.org/10.1016/j.jaac.2019.04.003
Kohls, Gregor ; Baumann, Sarah ; Gundlach, Malou ; Scharke, Wolfgang ; Bernhard, Anka ; Martinelli, Anne ; Ackermann, Katharina ; Kersten, Linda ; Prätzlich, Martin ; Oldenhof, Helena ; Jansen, Lucres ; van den Boogaard, Lisette ; Smaragdi, Areti ; Gonzalez-Madruga, Karen ; Cornwell, Harriet ; Rogers, Jack ; Pauli, Ruth ; Clanton, Roberta ; Baker, Rosalind ; Bigorra Gualba, Aitana ; Herpertz-Dahlmann, Beate ; Fernández-Rivas, Aranzazu ; Popma, Arne ; Stadler, Christina ; De Brito, Stephane ; Blair, James ; Freitag, Christine M. ; Fairchild, Graeme ; Konrad, Kerstin. / Investigating Sex Differences in Emotion Recognition, Learning, and Regulation among Youths with Conduct Disorder. In: Journal of the American Academy of Child and Adolescent Psychiatry. 2019 ; pp. 1-12.
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AU - Kohls, Gregor

AU - Baumann, Sarah

AU - Gundlach, Malou

AU - Scharke, Wolfgang

AU - Bernhard, Anka

AU - Martinelli, Anne

AU - Ackermann, Katharina

AU - Kersten, Linda

AU - Prätzlich, Martin

AU - Oldenhof, Helena

AU - Jansen, Lucres

AU - van den Boogaard, Lisette

AU - Smaragdi, Areti

AU - Gonzalez-Madruga, Karen

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AU - Pauli, Ruth

AU - Clanton, Roberta

AU - Baker, Rosalind

AU - Bigorra Gualba, Aitana

AU - Herpertz-Dahlmann, Beate

AU - Fernández-Rivas, Aranzazu

AU - Popma, Arne

AU - Stadler, Christina

AU - De Brito, Stephane

AU - Blair, James

AU - Freitag, Christine M.

AU - Fairchild, Graeme

AU - Konrad, Kerstin

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N2 - Objective: Conduct disorder (CD) is a serious neurodevelopmental disorder marked by notably higher prevalence rates for boys than girls. Converging evidence suggests that CD is associated with impairments in emotion recognition, learning, and regulation. However, it is not known whether there are sex differences in the relationship between CD and emotion dysfunction. Prior studies on emotion functioning in CD have so far been underpowered for investigating sex differences. Therefore, our primary aim was to characterize emotion processing skills in a large sample of girls and boys with CD compared to typically developing controls (TDCs) using a comprehensive neuropsychological test battery. Method: We included 542 youths with CD (317 girls) and 710 TDCs (479 girls), 9 to 18 years of age, from a European multisite study (FemNAT-CD). Participants completed three experimental tasks assessing emotion recognition, learning, and regulation, respectively. Data were analyzed to test for effects of group and sex, and group-by-sex interactions, while controlling for potentially confounding factors. Results: Relative to TDCs, youths with CD showed impaired emotion recognition (that was related to more physical and proactive aggression, and higher CU traits), emotional learning (specifically from punishment), and emotion regulation. Boys and girls with CD, however, displayed similar impairments in emotion processing. Conclusion: This study provides compelling evidence for a relationship between CD and deficient neurocognitive functioning across three emotional domains that have previously been linked to CD etiology. However, there was no support for sex-specific profiles of emotion dysfunction, suggesting that current neurocognitive models of CD apply equally to both sexes.

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