Intramolecular C-H insertion in ring-expanded N-heterocyclic carbenes

R S Holdroyd, M J Page, M R Warren, M K Whittlesey

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Mild heating of the ring-expanded N-heterocyclic Carbenes 7-Mes and 6-Mes results in intramolecular insertion of the carbene into an ortho-methyl C-H bond. In the presence of traces of acid, the resulting products ring-open to afford N-alkyl indoles. (C) 2009 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)557-559
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number3
DOIs
Publication statusPublished - Jan 2010

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